Analysis of Retinal Nerve Fibre Layer Changes in Cases of Phacomorphic Angle Closure Post Phacoemulsification
DOI:
https://doi.org/10.21276/xb7fc362Keywords:
Retinal nerve fibre layer, Optical coherence tomography, Phacomorphic angle closurec, Cup-disc ratioAbstract
Introduction: To investigate the retinal nerve fibre layer (RNFL) changes after an acute attack of phacomorphic angle closure. Methods: This prospective study involved 25 cases of phacomorphic angle closure that underwent phacoemulsification and intraocular lens insertion after intraocular pressure lowering. Apart from visual acuity and intraocular pressure (IOP), RNFL thickness was measured by optical coherence tomography (OCT) at 3–6 months post attack. Result: All cases had mean phacomorphic duration of <10 days. Postoperatively, best correct Snellen visual acuity was 0.42±0.23 and IOP at 6 months was 13.92 ± 2.41 mmHg. There was no difference RNFL between the attack and contralateral eye at 3 months post attack (both p = 0.102). At 6 months post attack, there was significant thinning in the average (p <0.001), superior (p =<0.001), and inferior (p = 0.001) RNFL. Patients with <5 days duration of phacomorphic angle closure are likely to have reasonable postoperative vision. Conclusion: An acute episode of phacomorphic angle closure can trigger an accelerated RNFL thinning despite normal IOP and open angles, most noticeable in the superior and inferior quadrants, occurring between 3 and 6 months post attack. There is a need of long term follow up of such patients.
Downloads
References
Pradhan D, Hennig A, Kumar J, Foster A. A prospective study of 413 cases of lens-induced glaucoma in Nepal. Indian J Ophthalmol. 2001; 49:103-07.
McKibbin M, Gupta A, Atkins AD. J Cataract extraction and intraocular lens implantation in eyes with phacomorphic or phacolytic glaucoma. Cataract Refract Surg. 1996; 22:633-36.
Angra SK, Pradhan R, Garg SP. Cataract induced glaucoma: An insight into management Indian J Ophthalmol. 1991; 39:97-101.
Jain IS, Gupta A, Dogra MR, Gangwar DN, Dhir SP. Phacomorphic glaucoma: Management and visual prognosis. Indian J Ophthalmol. 1983; 31:648-53.
Mapstone R. Closed-angle glaucoma: Theoretical considerations. Br J Ophthalmol. 1974; 58:36-40.
Prajna NV, Ramakrishnan R, Krishnadas R, Manoharan N. Lens induced glaucomas--visual results and risk factors for nal visual acuity. Indian J Ophthalmol 1996; 44: 149-155.
Schumer RA, Camras CB, Mandahl AK. Putative side effects of prostaglandin analogs. Surv Ophthalmol 2002; 47 Suppl 1: S219.
Ritch R, Tham CC, Lam DS. Argon laser peripheral iridoplasty (ALPI): an update. Surv Ophthalmol 2007; 52:279-288.
Rijal AP, Karki DB. Visual outcome and IOP control after cataract surgery in lens induced glaucomas. Kathmandu Univ Med J (KUMJ) 2006; 4:30-33.
Lee JW, Lai JS, Lam RF, Wong BK, Yick DW, et al. Retrospective analysis of the risk factors for developing phacomorphic glaucoma. Indian J Ophthalmol 2011; 59:471-474.
Tham CC, Lai JS, Poon AS, Chan JC, Lam SW, et al. Immediate argon laser peripheral iridoplasty (ALPI) as initial treatment for acute phacomorphic angle-closure (phacomorphic glaucoma) before cataract extraction: a preliminary study. Eye (Lond) 2005; 19: 778-783.
Lee JW, Lai JS, Yick DW, Tse RK. Retrospective case series on the long- term visual and intraocular pressure outcomes of phacomorphic glaucoma. Eye (Lond) 2010; 24:1675-1680.
Yip PP, Leung WY, Hon CY, Ho CK. Argon laser peripheral iridoplasty in the management of phacomorphic glaucoma. Ophthalmic Surg Lasers Imaging 2005; 36: 286-291.
Lee JW, Lai JS, Yick DW, Yuen CY. Prospective study on retinal nerve bre layer changes after an acute episode of phacomorphic angle closure. Int Ophthalmol 2012 32:577-582.
Aung T, Husain R, Gazzard G, et al Changes in retinal nerve fiber layer thickness after primary acute angle closure. Ophthalmology. 2004;111(8):1475-1479.
Tsai JC, Chang HW. Scanning laser polarimetry in patients with acute angle-closure glaucoma. Eye. 2004;18:9-14.
Sowka J. Phacomorphic glaucoma: case and review. Optometry 2006; 77:586-589.
Yoles E, Schwart Z. Potential neuroprotective therapy for glaucomatous optic neuropathy. SurvOphthalmol. 1998; 42:367-372.
Dada T, Kumar S, Gadia R, Aggarwal A, Gupta V, et al. Sutureless single-port transconjunctival pars plana limited vitrectomy combined with phacoemulsi cation for management of phacomo
Downloads
Published
Issue
Section
License
Copyright (c) 2024 International Archives of BioMedical and Clinical Research
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors are required to sign and submit the completed “Copyright transfer Form” upon acceptance of publication of the paper. This is determined by a publishing agreement between the author and International Archives of Biomedical and Clinical Research. These rights might include the right to publish, communicate and distribute online. Author(s) retain the copyright of their work. International Archives of Biomedical and Clinical Research supports the need for authors to share, disseminate and maximize the impact of their research.