A Prospective Study on Drug Utilization Pattern of NSAIDs in Patients Attending Orthopaedics OPD of a Tertiary Care Hospital

  • Manish Jain Associate professor, Department of Pharmacology, Pacific Medical College and Hospital, Udaipur.
  • Trilok Patil Associate professor, Department of Microbiology, Pacific Institute of Medical Sciences, Udaipur.
Keywords: NSAIDs, GI toxicity, COX-1, COX-2, Orthopaedics.

Abstract

Background: The objective of this study was to analyse the prescribing pattern of NSAIDs in patients attending Orthopaedics OPD and to analyse the correlation between the use of selective COX-2 inhibitors and older conventional NSAIDs in the pattern of current practice. Methods: This Prospective study was conducted on Patients visiting Orthopaedics OPD of Pacific Medical College and Hospital, Udaipur, during 6 month study period. Individual data was collected in a preformed format and was analyzed on parameters such as demographic profile and NSAID's usage pattern. Results: 180 patients were selected on the basis of inclusion and exclusion criteria. Around 417 drugs were prescribed, out of which 302 were oral, 39 were topical (Table No.2). Out of 417 drugs, total number of systemic NSAID's used were 302 [72.2%]. Of these 185 (56.2%) were used as monotherapy and 144 (43.7%) were used as fixed dose combinations (FDC). Among monotherapy 103 (55.68 %) were non-selective and 82 (44.32 %) were selective COX inhibitors.

Conclusion: The result of this study suggests that the frequent use of selective COX-2 inhibitors although conventional non-selective NSAIDs topped the list of various selective and non-selective NSAIDs. Concomitant gastro protectives were also used. Fixed dose combinations were also prescribed.

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Published
2016-09-28
How to Cite
1.
Jain M, Patil T. A Prospective Study on Drug Utilization Pattern of NSAIDs in Patients Attending Orthopaedics OPD of a Tertiary Care Hospital. IABCR [Internet]. 28Sep.2016 [cited 24Jul.2019];2(3):55-7. Available from: https://iabcr.org/index.php/iabcr/article/view/167