A Comparative study on Adenosine and Magnesium Sulphate with Bupivacaine in Infraclavicular infusion for Postoperative Analgesia

  • Manoj Kumar Upadhyay Associate Professor, Dept. of Anaesthesiology, Govt. Medical College, Azamgarh UP, India
  • Anurag Agarwal Associate Professor Dept. of Emergency Medicine, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow
  • Chandrashekhar Singh Associate Professor, GSVM Medical College, Kanpur
  • Rajiv Ratan Singh Associate Professor, Dept. of Emergency Medicine, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow.
  • Shivshankar Tripathi associate Professor, Dept. of Emergency Medicine, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow
  • Deepak Malviya HoD Dept. of Emergency Medicine, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow
Keywords: Bupivacaine, Adenosine, Magnesium Sulphate, Brachial plexus block.

Abstract

Background: Brachial plexus piece has reformed the field of regional anaesthesia for upper limb surgeries. Infraclavicular subcoracoid approach gives complete block without significant difficulties. Aim: To compare the additives adenosine and magnesium sulphate with bupivacaine in infraclavicular infusion for upper limb surgeries and postoperative analgesia. Materials & Methods: This Prospective study was done at the Department of Anaesthesiology, Govt. Medical College, Azamgarh. Around 24 patients scheduled for elective unilateral upper limb surgeries involving distal arm/ elbow/ forearm/hand divided into two groups A (n-12) and B (n-12) randomly. Group A - adenosine 6mgs with 28 ml 0.5% bupivacaine bolus followed by infusion of 0.25% bupivacaine 28ml with 6mgs of adenosine (2ml) at a rate of 5ml/hr. Group B - magnesium sulphate 75 mgs (in 2ml) with 28ml of 0.5% bupivacaine bolus followed by infusion of 0.25% bupivacaine 28ml with 75mgs of magnesium sulphate (in 2ml) at a rate of 5ml/hr in USG guided placement of infraclavicular catheter.

Results: Our Study revealed  that  Group  A  had a  faster Onset time of sensory and motor block and faster recovery when compared to group B. Group A needed more rescue analgesia than group B. Conclusion: The addition of magnesium sulphate as an additive to bupivacaine in brachial plexus block may be a better choice when prolonged postoperative analgesia is required.

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References

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Published
2018-03-21
How to Cite
1.
Upadhyay M, Agarwal A, Singh C, Singh R, Tripathi S, Malviya D. A Comparative study on Adenosine and Magnesium Sulphate with Bupivacaine in Infraclavicular infusion for Postoperative Analgesia. International Archives of BioMedical and Clinical Research [Internet]. 21Mar.2018 [cited 22Apr.2018];4(1):124-6. Available from: https://iabcr.org/index.php/iabcr/article/view/287