Importance of Synovial Biopsy of Knee Joint in the Diagnosis of Various Joint Disorders

Authors

  • Mohkam Singh Assistant Professor, Dept. of Orthopaedics, Krishna Mohan Medical College & Hospital, Mathura, U.P, India. Author
  • Rakesh Kumar Gupta Assistant Professor, Dept. of Orthopaedics, Krishna Mohan Medical College & Hospital, Mathura, U.P, India. Author

DOI:

https://doi.org/10.21276/qq7jnb85

Keywords:

synovial biopsy, Histo-pathologial findings, rheumatoid factor

Abstract

Background: Rheumatoid arthritis hardly causes diagnostic problems when presented typically. Generally, difficulties arise when atypical clinical presentation is related with non-contributory preliminary investigations. Arthritis is an important cause of morbidity.

Methods: In this study 60 total numbers of cases were included. This study was conducted in the Department of Orthopedics in K M Medical College & Hospital, Mathura. The duration of study was over a period of one year.

Result: This result revealed that 40% cases were suffering from Chronic non -specific synovitis, 31.6% Rheumatoid arthritis, 6.7% Septic Arthritis & Osteoarthritis, 5% Gout & Synovial (osteo) chondro mitosis,3.3% Synovial sarcoma, 1.6% Giant cell tumor of tendon sheath

Conclusion: This study concludes that Diagnostic method like immune-histological methods can be used to eliminate the “non-specificity”. It is also useful in achieving a better specific diagnosis.

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References

Ropes MW, Bauer W. Synovial Fluid Changes in Joint Disease. Cambridge, Mass: Harvard University Press; 1953.

Baeten D, van den Bosch F, Elewaut D, Stuer A, Veys EM, De Keyser F. Needle arthroscopy of the knee with synovial biopsy sampling: Technical experience in 150 patients. Clin Rheumatol 1999;18:434‑41.

To assess the incidence of various joint diseases in the present study.

MISGAR et al. The problems in the diagnosis of chronic synovitis of the knee.journal of indian medical association 1978 ; 70 ; 6: 132 -135.

SCHUMACHER HR AND KULPA JP et al. Needle biopsy of synovial membrane experience with parkar – pearson technique. new england journal of medicine 1972 ; 286 : 416 - 419.

NORMAN S COOPER et al. Diagnostic specificity of synovial lesions. Journal of human pathology 1981; 12 part 4: 314-328.

ABHAYANKAR SC et al. Histopathological study of synovium in chronic joint diseases. indian journal of pathology and micro biology 1987 ; 30 : 1-5.

GOLDEN BERG et al. Synovial membrane histopathology in the differential diagnosis of rheumatoid arthritis, gout, Psuedogout, SLE, infective arthritis and degenerative joint diseases. journal of indian medical association 1978; 57 part 3 : 325 – 329.

Published

20.03.2024

Issue

Section

ORIGINAL ARTICLES ~ Orthopaedics

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