Screening of Gestational Diabetes among Women Visiting Metabolic Clinic in the Department of Biochemistry of a Medical College in Eastern U.P
Background: Gestational diabetes mellitus (GDM) is a diabetic metabolic disorder that occurs in 4% of all pregnant women and 14% of ethnic groups with more prevalence of type II diabetes. It can be defined as increased or abnormal insulin resistance, decreased insulin sensitivity or glucose intolerance with first diagnosis during pregnancy. Aims/Objectives: 1. To find out prevalence of GDM. 2. To study associated risk factors.
Methods: The study was conducted at the metabolic clinic; in the department of Biochemistry located at SIMS, Hapur. A semi-structured pretested questionnaire was used for data collection. Following the DIPSI guidelines, patients with plasma glucose values >140 mg/dl were labeled as GDM. Statistical methods used were OR (CI95%), percentage, Chi square.
Results: ‘Out of 500, 6.72% had GDM. Among all GDM patients, 64.71% had age more than 30 years, 70.59% had BMI more than 25, 41.18% had gravida more than 3 and p- value was significant with regard to age and BMI. P value was found to be significant for risk factors namely positive family history of Diabetes Mellitus, history of big baby and presence of more than one risk factor.
Conclusion: GDM is associated with high BMI, early pregnancy loss, family history of DM and previous history of big baby and there could be more than one risk factor. Thus universal screening followed by close monitoring of the pregnant women for early detection of GDM may help improving maternal and fetal outcomes.
2. Davey RX, Hamblin PS. Selective versus universal screening for gestational diabetes mellitus: An evaluation of predictive risk factors.Med J Aust. 2001;174:118–21. [PubMed]
3. Opara PI, Jaja T, Onubogu UC. Morbidity and mortality amongst infants of diabetic mothers admitted into a special care baby unit in Port Harcourt, Nigeria. Ital J Pediatr. 2010;36:77. [PMC free article] [PubMed]
4. Otolorin EO, Famuyiwa OO, Bella AF, Dawodu AH, Adelusi B. Reproductive performance following active management of diabetic pregnancies at the university college hospital, Ibadan, Nigeria. Afr J Med Med Sci.1985;14:155– 60. [PubMed]
5. Balaji V, Balaji M, Anjalakshi C, Cynthia A, Arthi T, Seshiah V. Diagnosis of gestational diabetes mellitus in Asian-Indian women. Indian J EndocrinolMetab. 2011;15:187–90. [PMC free article] [PubMed]
6. Wahi P, Dogra V, Jandial K, Bhagat R, Gupta R, Gupta S, et al. Prevalence of gestational diabetes mellitus and its outcomes in Jammu region. J Assoc Physicians India. 2011;59:227–30. [PubMed]
7. Gajjar F, Maitra K. Intrapartum and perinatal outcomes in women with gestational diabetes and mild gestational hyperglycemia. J Obstet Gynaecol India. 2005;55:135–7.
8. Sheshia V, Balaji V, Madhuri S. Balaji, Sanjeevi CB, Anders Green. Gestational Diabetes Mellitus in India. J Assoc Physicians India, 2004;52:707.
9. Family Welfare Statistics of India 2011. Statistics Division, Ministry of Health & Family Welfare, GOI.
10. Special bulletin on Maternal Mortality in India 2010-12. SRS, Office of Registrar General, India.
11. Sheshia V, Balaji V, Madhuri S. Balaji, Aruna Sekar, Sanjeevi CB, Anders Green. One step procedure for screening and diagnosis of Gestational Diabetes Mellitus. J Obstet Gynaecol. India 2005;55:525-29.
12. Parikh Pallav, Shah Asha, Joshi Dinesh, Shah Rushit. Prevalence of gestational diabetes at tertiary care center. International Journal of Scientific and Research Publication 2014;4(9):1-3
13. Zargar AH, Sheikh MI, Bashir MI, Masoodi SR, Laway BA, Wani AI, et al. Prevalence of gestational diabetes mellitus in Kashmiri women from the Indian Subcontinent. Diabetes Res ClinPract. 2004;66:139–45.
14. PriyankaKalra, Chetan Prakash Kachhwaha, and Hilda Victoria Singh. Prevalence of gestational diabetes mellitus and its outcome in western Rajasthan. Indian J EndocrinolMetab. 2013 Jul-Aug; 17(4): 677–680.
15. Meena Rajput, Mohan Bairwa, and Rajesh Rajput. Prevalence of gestational diabetes mellitus in rural Haryana: A community-based study. Indian J EndocrinolMetab. 2014 May-Jun; 18(3): 350–354.
16. Verma A K, Singh B, Mengi V. Gestational diabetes in rural women of Jammu. Indian J Community Med 2008;33:54-5.
17. Rajesh Rajput, Yogesh Yadav, Smiti Nanda, Meena Rajput. Prevalence of gestational diabetes mellitus & associated risk factors at a tertiary care hospital in Haryana. Indian J Med Res. 2013 Apr; 137(4): 728–733.
18. Pikee Saxena, Swati Tyagi, Anupam Prakash, Aruna Nigam, Shubha Sagar Trivedi. Pregnancy Outcome of Women With Gestational Diabetes in a Tertiary Level Hospital of North India. Indian J Community Med. 2011 Apr-Jun; 36(2): 120–123.
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