Evaluation of Hematological Abnormalities in HIV Patients in Kosi Zone of Bihar

  • Abhishek Kumar Post Graduate Trainee, Department of Medicine, Katihar Medical College, Katihar.
  • P.K. Agrawal Professor, Department of Medicine, Katihar Medical College, Katihar.
  • Vishal Parmar Associate Professor, Department of Medicine, Katihar Medical College, Katihar.
  • Faiyaz Alam Assistant Professor, Department of Medicine, Katihar Medical College, Katihar.
  • Farogh Haidry Post Graduate Trainee, Department of Medicine, Katihar Medical College, Katihar.
  • Yogesh Kumar Dubey Post Graduate Trainee, Department of Medicine, Katihar Medical College, Katihar.
  • Saad Bin Saif Post Graduate Trainee, Department of Medicine, Katihar Medical College, Katihar.
Keywords: HIV, Thrombocytopenia, Leucopenia

Abstract

Background: Hematological abnormalities are among the most common complications of HIV.  Anaemia is the most common hematological abnormality in HIV patients, and is strongly associated with the progression of the disease, followed by leucopenia and thrombocytopenia. The objective of the study is to find out the magnitude & type of hematological abnormalities and its correlation to CD4 Count.  Methods: The study was done on 80 HIV patients, above the age of 15 yrs, including both males and females, attending ART Centre, at Katihar Medical College, Katihar, Bihar. Various haematological parameters were recorded and studied with respect to CD4 count. Results: Among the total patients, 57.5% had anaemia, 23.75% had leucopenia and 12.5% had thrombocytopenia. The magnitude of these abnormalities were directly proportional to low CD4 counts. Results: Among the total patients, 57.5% had anaemia, 23.75% had leucopenia and 12.5% had thrombocytopenia. The magnitude of these abnormalities were directly proportional to low CD4 counts. 

Conclusions: These hematological parameters can be used to assess the severity and progression of HIV as they are directly associated with CD4 count. Anaemia being the single most independent factor associated with high mortality. Aggressive treatment of these haematological abnormalities can lead to substantial decline in morbidity and mortality associated with HIV patients.

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Published
2017-12-20
How to Cite
1.
Kumar A, Agrawal P, Parmar V, Alam F, Haidry F, Dubey Y, Saif S. Evaluation of Hematological Abnormalities in HIV Patients in Kosi Zone of Bihar. IABCR [Internet]. 20Dec.2017 [cited 20Aug.2018];3(4):44-6. Available from: https://iabcr.org/index.php/iabcr/article/view/16