Comparison of computed tomography and magnetic resonance imaging based target delineation in radiotherapy planning of central nervous system tumors ( High grade gliomas).
DOI:
https://doi.org/10.21276/8wfm0219Abstract
Aim of study : The study was designed to assess and analyze the difference in tumor volumes depicted on computed tomography (CT) and magnetic resonance (MRI) and their effect on the treatment planning.
Materials and methods: twenty -five patients with high grade glioma who had underwent surgical resection and reffered for radiation treatment were taken in the study. CT and MRI imaging were done for all the patients with 1.25 mm thickness. the CT and MRI tumor volumes were delineated and comparision was done between them.
Results: The mean and median of GTV on CT scan were 70.82 and 65.65 respectively. The mean and median of GTV on MRI were 91.11 and 76.54 respectively. A linear relationship between CT and MRI volumes with correaltion coefficient of r=0.93 and MRI shows 1.19 times more volume when comparedwith CT volumes.
Conclusion : The study shows that MRI is an important modality to delineate the brain tumor to avoid the geographical miss and under dosage of the tumor.
key words: high grade glioma, computed tomography, magnetic resonance imaging.
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