A Study to Find Hemodynamic Changes and Complication Occurring with Propofol and Etomidate During General Anaesthesia
DOI:
https://doi.org/10.21276/x06x9z82Keywords:
Propofol, Etomidate, General Anaesthesia.Abstract
Background: The present study was undertaken for assessing hemodynamic changes and complication occurring with propofol and etomidate during general anaesthesia.
Materials & Methods: Sixty patients who were schedule to undergo surgical procedure under general anaesthesia were enrolled in the present study. Random division of patients was done into two study groups as follows: Group A: 30 Patients who received Propofol, and Group B: 30 Patients who received Etomidate group. All the patients were premedicated with alprazolam 0.25 mg and ranitidine 150 mg one night before the surgery. All the hemodynamic parameter was recorded during the surgery procedure. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software.
Results: Incidence of complications was slightly higher among subjects of group A. Mean arterial pressure among patients of group A at baseline, at induction, at laryngoscopy, after one minute, after five minutes and after fifteen minutes were 92, 76, 105, 101, 92 and 95 respectively. Mean arterial pressure among patients of group B at baseline, at induction, at laryngoscopy, after one minute, after five minutes and after fifteen minutes were 95, 89, 95, 97, 94 and 96 respectively. While analysing statistically, it was seen that mean arterial pressure and mean heart rate are significantly altered at different time intervals among subjects of group A.
Conclusion: Etomidate had superior efficacy in comparison to propofol as an anaesthetic agent.
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