Assessment of C Reactive Proteins Levels in Hypertensive Patients of Tertiary Care Teaching Hospital in Central India
Background: The present study was conducted for assessing C reactive proteins levels in hypertensive patients
Materials & Methods: The study included 100 hypertension cases and 100 controls who met the inclusion requirements. Data were collected through interview and review of medical records. Newly diagnosed 100 treatment naive cases of Essential Hypertension attending medical OPD and admitted in medical wards was included in the study. Patients diagnosed as hypertensive by physician were enrolled in the study. For each case one control was selected. History of co-morbid illness, prolonged co-morbidity, and history of hypertension was evaluated. All subjects had 5 mL of blood drawn into serum tubes after an overnight fast. After letting the blood clot for 15 minutes at 3000 RPM, the serum was centrifuged out. C-reactive protein levels in the blood were checked right away. CRP levels were evaluated using Immunoturbidimetry. The data was analysed by using descriptive and inferential statistics.
Results: The mean CRP in Cases was more (5.38 ± 1.62) as compared to Controls (1.13 ± 0.48) found statistically significant. (By Un-paired T test; p>0.05). The above table shows association of type (NYHA) of hypertension and CRP among cases. The mean CRP in Stage II was more (6.13 ± 1.28) as compared to Stage I (5.19 ± 1.78) shows statistically significant.
Conclusion: This study confirmed the function of CRP and established its significance as a marker for early detection and prevention of myocardial infarction in hypertensive patients.
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