Bilateral Nevus of Ota with Phakomatosis pigmentovascularis treated with 1064 nm picosecond laser: A case report

Neha Mehta; Vikas Malgotra; Md Raihan; Vikrant Choubey; Sohini Saha

Neha Mehta
Vikas Malgotra Rama Medical College Hospital and Research Centre Hapur
Md Raihan
Vikrant Choubey
Sohini Saha

Keywords: Nevus of Ota, Phakomatosis pigmentovascularis, Picosecond laser, 1064 nm laser

Abstract

Nevus of Ota is an uncommon dermal melanosis in the Indian subcontinent and is rarely associated with capillary malformations, classified as type II phakomatosis pigmentovascularis (PPV). It usually presents unilaterally as mottled, slate blue, or dark brown macules; bilateral presentation is only seen in a few cases. A 20-year female presented to Dermatology OPD of a tertiary hospital with bilateral nevus of Ota involving the cheeks, temples, nose, forehead, and sclera of the eyes for one year. She also had a port wine stain on the right arm, forearm, back, bittock, and thigh since birth without any other systemic involvement. We treated nevus of Ota with six sessions of 1064 nm picosecond laser every month at 0.8 J/cm² with significant improvement in the appearance of the lesions and no adverse effects. This case highlights the importance of thoroughly examining pigmented lesions for additional cutaneous findings and the potential use of a 1064 nm picosecond laser to treat such lesions.

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References

1. Maguire J, Holt D. Nevus of Ota – an intraoral presentation: a case report. J Med Case Rep. 2019;13(1):174.
2. Alsaif F, Alshahwan H. Bilateral nevus of Ota associated with Turner syndrome. J Saudi Soc Dermatology Dermatologic Surg. 2011;15(1):33–6.
3. Brittain P, Walsh EJ, Smidt AC. Blotchy baby: A case of phakomatosis pigmentovascularis. J Pediatr. 2013;162(6):1293-1293e1.
4. Yang Y, Guo X, Xu J, Ye Y, Liu X, Yu M. Phakomatosis Pigmentovascularis Associated With Sturge–Weber Syndrome, Ota Nevus, and Congenital Glaucoma. Medicine (Baltimore). 2015;94(26):e1025.
5. Solanki J, Gupta S, Sharma N, Singh M, Bhateja S. Nevus of Ota”- A Rare Pigmentation Disorder with Intraoral Findings. J Clin DIAGNOSTIC Res. 2014;8(8):ZD49–50.
6. Verma SB, Desai HK, Shah VN, Happle R. Phacomatosis cesioflammea with cutis marmorata-like lesions and unusual extracutaneous abnormalities: Is it a distinct disorder? Indian J Dermatol. 2017;62(2):207.
7. Nam JH, Kim HS, Choi YJ, Jung HJ, Kim WS. Treatment and classification of nevus of ota: A seven-year review of a single institution’s experience. Ann Dermatol. 2017;29(4):446–53.
8. MA H, Liao M, Qiu S, Luo R, Lu R, Lu C. The case of a boy with nevus of Ota, extensive Mongolian spot, nevus flammeus, nevus anemicus and cutis marmorata telangiectatica congenita: a unique instance of phacomatosis pigmentovascularis. An Bras Dermatol. 2015;90(3 suppl 1):10–2.
9. Watanabe S, Takahashi H. Treatment of Nevus of Ota with the Q-Switched Ruby Laser. https://doi.org/101056/NEJM199412293312604. 1994;331(26):1745–50.
10. Lowe NJ, Wieder JM, Sawcer D, Burrows P, Chalet M. Nevus of Ota: Treatment with high energy fluences of the Q-switched ruby laser. J Am Acad Dermatol. 1993;29(6):997–1001.
11. Kono T, Nozaki M, Chan HH, Mikashima Y. A retrospective study looking at the long-term complications of Q-switched Ruby laser in the treatment of nevus of Ota. Lasers Surg Med. 2001;29(2):156–9.
12. Ge Y, Yang Y, Guo L, Zhang M, Wu Q, Zeng R, et al. Comparison of a picosecond alexandrite laser versus a Q-switched alexandrite laser for the treatment of nevus of Ota: A randomized, split-lesion, controlled trial. J Am Acad Dermatol. 2020;83(2):397–403.
13. Bennardo L, Cannarozzo G, Tamburi F, Patruno C, Provenzano E, Nisticò SP. Picosecond Q-Switched 1064/532 nm Laser in Tattoo Removal: Our Single Center Experience. Appl Sci. 2021;11(20):9712.
14. Williams NM, Gurnani P, Long J, Reynolds J, Pan Y, Suzuki T, et al. Comparing the efficacy and safety of Q-switched and picosecond lasers in the treatment of nevus of Ota: a systematic review and meta-analysis. Lasers Med Sci. 2021;36(4):723–33.