A Malignant Granular Cell Tumour with an Unusual Presentation: A Rare Case Report

  • Kirti Rajput Junior Resident, Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University,Uttar Pradesh, India
  • Bushra Siddiqui Assistant Professor, Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Uttar Pradesh, India
  • Shahbaz Habib Faridi Assistant Professor, Department of General Surgery, Jawaharlal Nehru Medical College, Aligarh Muslim University,Uttar Pradesh, India
  • Saqib Ahmed Senior Resident , Department of Pathology, Shri Guru Ram Rai Institute Of Medical and Health Sciences , Dehradun, Uttarakhand,India

Abstract

A granular cell tumour is a tumour of neural origin and is mostly benign and rarely malignant and commonly found in the skin, oral cavity or digestive tract. This report describes a case of a 23-year-old female with a palpable painless mass on the back near the left axilla with progressive growth. While her laboratory tests and radiological were within normal limits histopathological examination revealed round to polygonal PAS positive atypical cells with large vesicular nuclei and coarsely granular cytoplasm along with foci of spindling and necrosis which on IHC were S-100 and CD68 positive and negative for cytokeratin, desmin, EMA. Thus, rendering a diagnosis of a malignant granular tumour of primary origin. This case highlights the importance of accurate histopathological examination to recognise and further categorization of Granular cell tumours along with clinical and radiological correlation.

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Published
2022-12-06
How to Cite
1.
Rajput K, Siddiqui B, Faridi SH, Ahmed S. A Malignant Granular Cell Tumour with an Unusual Presentation: A Rare Case Report . Int Arch BioMed Clin Res [Internet]. 2022Dec.6 [cited 2023Feb.1];8(3):CR4-CR6. Available from: https://iabcr.org/index.php/iabcr/article/view/814