To study the Prevalence and Antibiotic Sensitivity Pattern of Isolated Bacteria from the Blood, Urine, CSF and Pus Samples in a Tertiary Care Teaching Hospital
DOI:
https://doi.org/10.21276/32mnf586Keywords:
Cerebrospinal fluid, Escherichia coli, Urinary tract infectionsAbstract
Introduction: The worldwide escalation in both community- and hospital-acquired antimicrobial-resistant bacteria is threatening the ability to effectively treat patients, emphasizing the need for continued surveillance, more appropriate antimicrobial prescription, prudent infection control, and new treatment alternatives.
Objective: To study the prevalence of bacteria from the different samples (Blood, Urine, CSF, PUS) and to examine the antibiotic sensitivity pattern of isolated organisms.
Methods: Around n=150 samples of Urine, Blood, CSF and Pus sample were collected from the patient attending Teerthanker Mahaveer medical Hospital college and Research Centre.
Results: Out of 150 clinical samples, highest number of isolates were gram-positive, Staphylococcus aureus n=47 (31.33%) followed by E. Coli n=37(24.66%), Klebseilla n=33(22.00%), Pseudomonas n=11(07.33%). S. aureus was highly sensitive to Gentamycin (88.09%) and least sensitive to Co-trimoxazole (14.28%). Tobramycin & Linezolid were 95.23% sensitive followed by Amikacin (90.47%), Meropenem (90.47%), Levofloxacin (88.09%).
Conclusion: In our study Staphylococcus aureus to be most common isolates followed by Escherichia coli, Klebseilla, Pseudomonas, Citrobacter, Proteus.
Downloads
References
Antibiogram of clinical isolates from a healthcare infection Control Practices Advisory Committee (HICPAC)..Central for Disease Control and Prevention(CDC). Management of Multidrug-
Resistant Organisms in Healthcare Settings; 2006. Available from http://www.cdc.gov/hicpac/pdf/MDRO/MDROGGuideline2006.pdf
Diekma DJ, Beekman SE, Chapin KC et al. Epidemiology and
outcome of nosocomial and community onset bloodstream infection. J Clin Microbiol 2003; 41: 3655-60.
Young LS. Sepsis syndrome. In: Mandell GL, Bennett JE, Dolin R, eds. Principle and Practice of infectious diseases. Churchill Livingstone, 1995; 690-705.
Hussain, N., 2001. Prevalence and susceptibility pattern of urinarypathogens.Biomedica;18:76-79.
Foxman, B., 2003.Epidemiology of urinary tract infections: incidence, morbidity and economic costs. Dis Mon., 49: 53-70.
Gales, A.C., H.S. Sader and R.N. Jones, 2002. Urinary tract infection trends in Latin Americans hospitals. Diagon. Microbial. Infect. Dis., 44: 289-299.
Devmurari D, Kamal CM, Singh SN, Kumar A. Ofloxacin and Nitrofurantoin sensitivity pattern In Patients of Urinary Tract Infection (UTI) at a tertiary care teaching hospital. Int Arch BioMed Clin Res. 2015 Aug; 1(1):17-22
Thomas, J.G., 1995. Urinary tract inections. In: diagnostic Microbiology. (Eds Mohan, C. R. and G. Manuselis), pp: 950-969.
Patel BV, Patel PG, Raval PN, Patel MH, Patel PH, Vegad MM. Bacteriological Profile and Antibiogram of Gram Negative Organisms Isolated from Medical and Neurology Intensive Care Unit with Special Reference To Multi-Drug Resistant Organisms. Natl J Med Res. 2012; 2(3): 335-338.
Panta Kirtu, Ghimire Prakash et al;Antibiogram typing of gram negative isolates in different clinical samples of A Tertiary Hospital. Asian J Pharm Clin Res, Vol 6, Issue 1, 2013, 153-156
Downiel L, Armientol R, Subhil R, Kelly J, Clifford V, Duke T. Community-acquired neonatal and infant sepsis developing countries: efficacy of WHO’s currently recommended antibiotics systematic review and meta – analysis. (Arch dis Child doi:10.1136/archdischild-2012-302033).
Karki S, Rai GK, Manandhar R. Bacteriological Analysis and Antibiotic Sensitivity Pattern of Blood Culture Isolates in Kanti C hildren Hospital. J.Nepal Paediatr. Soc. 2010;Vol30(2):94-97.
Asad U Khan and Mohd S Zaman: Multiple drug resistance pattern in urinary tract infection patients in Aligarh; Biochemical Research 2006;17(3):179-181.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 International Archives of BioMedical and Clinical Research
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors are required to sign and submit the completed “Copyright transfer Form” upon acceptance of publication of the paper. This is determined by a publishing agreement between the author and International Archives of Biomedical and Clinical Research. These rights might include the right to publish, communicate and distribute online. Author(s) retain the copyright of their work. International Archives of Biomedical and Clinical Research supports the need for authors to share, disseminate and maximize the impact of their research.
