Single Dose Extradural Analgesia Vs Bupivacaine and Lignocaine with Adrenaline: A Comparative Hospital Based Study in Solan

Authors

  • Mandeep Goma Assistant Professor, Department of Anaesthesiology, Maharishi Markandeshwar Medical College & Hospital, Solan, H.P Author

DOI:

https://doi.org/10.21276/08b59h84

Keywords:

Analgesia, Bupivacaine, Clonidine

Abstract

Background: Lignocaine and bupivacaine are mainly used local anaesthetics in the present day. Therefore, we are presenting a comparative study of single dose extradural analgesia with Bupivacaine and Lignocaine with adrenaline.

Methods: The study was carried out in 30 healthy subjects posted for lower abdominal, pelvic, perineal and lower limb surgeries. They were randomly divided into 2 groups. Group I and Group II. Group I (N=15): Received 20ml of 1.5% Lignocaine with adrenaline 1:200000. Group II (N=15): Received 20ml of 0.5% Bupivacaine.

Results: The mean times (with standard times) been extradural injection and onset of analgesia indicate that Lignocaine had a significantly quicker onset of action. Intra operative complications like hypotension, drowsiness, nausea and vomiting and post-operative complications like headache, back ache, nausea, vomiting, retention of urine and neurological sequelae were noted.

Conclusion: Lignocaine with adrenaline had a significantly quicker onset of action. Duration of analgesia produced by Bupivacaine was found to be significantly longer than that produced by Lignocaine with adrenaline.

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References

Miller, RD et al. Miller's Anesthesia, 7th edition, Churchill Livingstone: 2009 p 409, 1616-8.

Laishley RS, Morgan BM: A single dose epidural technique for cesarean section. Anaesthesia 1988; 43:100-3.

Curatolo M, Orlando A, Zbinden AM, Scaramozzino P, Venuti FS: A multifactorial analysis to explain inadequate surgical analgesia following extradural block. Br J Anaesth 1995; 75:274-81.

Bromage PR, Camporesi EM, Durant PA, Nielsen CH: Influence of epinephrine as an adjuvant to epidural morphine. Anesthesiology 1983; 58:257-62.

Bromage PR, El-Faqih S, Husain I, Naguib M: Epinephrine and fentanyl as adjuvants to 0.5% bupivacaine for epidural analgesia. Reg Anesth 1989; 14:189-94.

McLintic AJ, Danskin FH, Reid JA, Thorburn J: Effect of adrenaline on extradural anaesthesia, plasma lignocaine concentrations and the feto-placental unit during elective caesarean section. Br J Anaesth 1991;67:683-9.

Ilfeld B .Evidence of continuous regional anesthesia vs single shot. ESRA Abstracts. Regional Anesthesia and Pain Medicine 2014 ;39(5).

M.J.Watt, D.M.Rass, R.S.Atkinson. A double blind trial of bupivacaine and lignocaine .Latency and duration in extradural blockade.Anaesthesia1968;23:231.

Dr A K Sinha, Dr D C Punera, Dr Upalaria, Dr MeharBano, Dr Sagufta Ansari. Comparison of Intra-Operative ECG Variations (QRS and PR Interval Pro-longation) Between 0.25% Ropivacaine and 0.25% Bupivacaine in Patients Undergoing Lower Limb Surgery under Epidural Blockade. JMSCR 2016 ; 4(8): 12131- 38 .

Goring-Morris J , Russell IF. A randomised comparison of 0.5% bupivacaine with a lidocaine/epinephrine/fentanyl mixture for epidural top-up for emergency caesarean section after "low dose" epidural for labour. Int J Obstet Anesth. 2006

Apr;15(2):109-14.

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Published

07.04.2024

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Section

ORIGINAL ARTICLES ~ General Surgery

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