Fine Needle Aspiration Cytology (FNAC) Lymph Node - A Diagnostic Tool for Histopathological Diagnosis in a Tertiary Care Teaching Hospital

Authors

  • Pankaj Bansal Assistant Professor, Department of Pathology, Ananta Institute of Medical Science & Research Center, Rajsamand, Rajasthan Author
  • P M Parihar Assistant Professor, Department of Pathology, Geetanjali Medical College & Hospital, Udaipur, Rajasthan. Author

DOI:

https://doi.org/10.21276/01205775

Keywords:

FNAC, Lymphadenopathy, Metastatic carcinoma, Tubercular lymphadenitis

Abstract

Background: Fine Needle Aspiration Cytology (FNAC) is used to evaluate the nature of the lesion. Lymphadenopathy in head and neck region have wide spectrum etiology vary from benign reactive hyperplasia to tubercular granulomatous lesion to malignancy. The present study was undertaken to evaluate the sensitivity, specificity and predictive value in tuberculosis and metastatic carcinoma.

Methods: A total of 70 patients out of 180 patients at Geetanjali Medical College & Hospital, Udaipur, Rajasthan, who underwent FNAC were evaluated by histopathological examination for correlation. Aspiration smears and histopathological slides were evaluated and results were calculated for sensitivity, Specificity and predictive value.

Results: Reactive lymphadenitis was seen in 37 patients followed by tubercular granulomatous lymphadenitis in 17 patients and malignant lesions in 16 patients. Histology revealed 16 patients of tubercular lymphadenitis, 41 of reactive changes, 11 of metastasis in lymph nodes and 5 of lymphomas. Correlating the findings, we could achieve 100% sensitivity and 96.7% specificity for tubercular lymphadenopathy and for metastatic it was 98.5% and 100% respectively.

Conclusions: We have discovered FNAC an agreeable instrument in the conclusion of tubercular and harmful lymphadenopathy. FNAC utilized as a part of conjunction with clinical discoveries, radiological and research center examinations can be a financially savvy strategy for the determination of lymphadenopathy

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References

Frable WJ, Frable MA. Fine Needle Aspiration Biopsy revisited. Laryngoscope. 1982;92 (2): 1414.

Buley ID. Fine needle aspiration of lymph nodes. J clin patho. 1998; 51:881-5.

Orell SR, Sterer GF, Whitaker D. Fine needle aspiration cytology, 4thedition, Chirchill Livingston. 2005; 1-8,83-124.

MalakarD , Jajoo ILN, Swarup K,Gupta OP, Jain AK, Poflee VW. A clinical evaluation of Fine needle aspiration cytology in the diagnosis of lymphadenopathy. Ind. J. Tub. 1991;38:17.

Blackshaw A. Metastatic tumour in lymph nodes. In: Standfield AG, D'Ardenne, editors. Lymph node biopsy interpretation. London: Churchill Livingstone, 1987: 380-397.

Coyne JD, Banerjee SS, Menasche LP, Mene A. Granulomatous lymphadenitis associated with metastatic malignant melanoma. Histopathol. 1996;28(5):470-2.

Santini D, Pasquinelli G, Alberghini M, Martinelli GN, Taffurelli M. Invasive breast carcinoma with granulomatous response and deposition of unusual amyloid. J Clin Pathol. 1992;45(10):885-8.

Khurana KK, Stanley MW, Powers CN, Pitman MB. Aspiration cytology of malignant neoplasms associated with granulomas and granuloma-like features: diagnostic dilemmas. Cancer. 1998;84(2):84-91.

Gregori HB, Othersen HB, Moore MP. The significance of sarcoid-like lesions in association with malignant neoplasm. Am J Surg. 1962;104:577-86.

Tilak V, Dhadel AV, Jain R. Fine needle aspiration cytology of the head and neck masses. Indian J Pathol Microbiol.2002;45:23 9.

Rajwanshi A, Bhambani S, Das DK. Fine Needle Aspiration Cytology in the diagnosis of Tuberculosis; Diagn. Cytopathol. 1987;3(1):13.

Engzell U, Jakobbsen PA, Zajicek J. Aspiration biopsy of metastatic carcinoma in lymphnodes of the neck A review of 1101 consecutive cases; Act. Otolaryng. 1972;72:138.

Ross JE, Scanlon EF, ChristMA. Aspiration cytology of Head and Neck masses; Am. J. Surg; 1978;136:342.

Gupta SK, Dutta JK, Aikat M,Gupta BD. Evaluation of Fine needle biopsy technique in diagnosis of tumours.Ind. J. Can. 1975;12:257.

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Published

07.04.2024

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Section

ORIGINAL ARTICLES ~ General Surgery

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