Study of Malaria Parasite with Special Reference to Liver Function Test of the Patient Attending at TMU Hospital Moradabad (U.P)

Authors

  • Ratnendra Bisht Demonstrator, Department of Microbiology, KM Medical college Mathura (UP). Author
  • Madhubala Mishra Senior Demonstrator, Department of Microbiology, RNT Medical college Udaipur (RJ) Author
  • Sandhya Mishra Senior Demonstrator, Department of Microbiology, RNT Medical college Udaipur (RJ) Author

DOI:

https://doi.org/10.21276/f6g2gs76

Keywords:

plasmodium, liver function, malaria

Abstract

Background: Malaria is an important infectious vector borne disease caused by a Plasmodium species. Liver involvement in severe Plasmodium falciparum infection is commonly a significant cause of morbidity and mortality among humans. Objective: In this study, we show the correlation of malaria positive cases with liver derangement. Methods: The present study had been conducted in Teerthankar Mahaveer Medical college Hospital and Research Center, Moradabad, U.P. from February 2014 to January 2015  on both IPD & OPD patients .Results: The present study included  200 clinically suspected cases of Malaria with derange Liver function. 67.5% patients show increased level of Total and indirect bilirubin followed by 45% of patient shows increased level of direct bilirubin. 27.5% patient’s shows increased level SGPT followed by 40% of SGOT. Conclusions: Deranged liver functions are commonly seen as a complication of severe malarial infection.

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References

White NJ Berman JG. Malaria and Babesiosis - Diseases caused by red blood parasite. In: Harrison's Principles of Internal medicine. Ed: Braunwald E, Fauci AS, Kasper DL, Hasure SL, Longo DL, Hauser SL, Longo DL, Jameson JL.16th edn. Vol 1. New York: Mc Graw - Hill 2005; 1218 - 1232.

Richmond A, Desmond O, Acheampong, Johnson NB, Margaret. Sarpong- Baidoo, Ekene K, et. Al. Typhoid- Malaria Co- infection in Ghana.Euro.J. Exper Bio. 2011,1(3):1-6.

K.Park.Arthopod- Born Infections.In:- Epidimiology of communicable diseases. Park,s Text Book of Preventive and social medicine. 21th edn., Jabalpur: Banarasidas Bhanot Publication, 2011. P231- 243.

World Health Organization (2010) World malaria report 2010 Available: http://whqlibdoc.who.int/publications/2010/9789241564106_eng.pdf Accessed 14 September 2011.

Leslie T, Mayan MI, Hasan MA, Safi MH, Klinkenberg E, Whitty CJ, Rowland M (2007) Sulfadoxine-pyrimethamine, chlorproguanil-dapsone, or chloroquine for the treatment of Plasmodium vivax malaria in Afghanistan and Pakistan: a randomized controlled trial. JAMA 297: 2201-2209.

Khatoon L, Baliraine FN, Bonizzoni M, Malik SA, Yan G (2009) Prevalence of antimalarial drug resistance mutations in Plasmodium vivax and P. falciparum from a malaria-endemic area of Pakistan. Am J Trop Med Hyg 81:525-528.

Muddaiah M and Prakash PS (2006) A study of clinical profile of malaria in a tertiary referral centre in South Canara. J Vector Borne Dis 43: 29-33.

Yuda M and Ishino T et al. Liver invasion by malarial parasites. Cellular Microbiol 2004; 6 (12):1119‐1125

Nadeem M, Ali N and Qamar MA et al. Hematological findings in acute malarial infection. Biomedica 2002; 18:62‐65.

Donald and Krogstad. et al. Plasmodium species (Malaria). Mandell Doughlas and Bennetts. 5th Edition. 1995; pp 2817‐2830.

Molyneux ME, Looareesuwan S, Menziee IS and Grainger SL et al. Reduced hepatic blood flow and intestinal malabsorption in severe falciparum malaria. Am J Trop Med Hyg 1989; 4‐(5):470‐476

Baheti R, Laddha P and Gehlot RS. et al. Liver Involvement in falciparum malaria - A histo‐pathological analysis. JIACM 2003; 4(1):34‐8.

Waitumbi JN, Opollo MO and Muga RO et al. Red cell surface changes and erythrophagocytosis in children with severe plasmodium falciparum anemia. Blood 2000; 95(4):1481‐1486.

Kochar DK, Singh P, Agarwal P, Kochar SK, Pokharna R, Sareen PR. Malarial Hepatitis. J Assoc Phys India 2003;51: 1069-72.

Anand AC, Puri P. Jaundice in Malaria. J Gastroenterol Hepatol

;20:1322-32. )

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Published

07.04.2024

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Section

ORIGINAL ARTICLES ~ General Surgery

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