Histopathological Diagnosis amongst Subjects of Liver Diseases Reporting to the Pathology Department: An Institutional Based Study
Background: Chronic liver diseases are one of the greatest cause deaths around the world, representing around 1.03 million deaths each year. The aim of the present study was to evaluate the histopathological diagnosis of subjects with liver disease.
Materials and methods: The present study was conducted in a prospective fashion enrolling 120 subjects reporting to the Department of Pathology, SMS Medical College & Hospital, Jaipur, Rajasthan (India) with liver disorders. There were 60 cases of hepatitis either viral or non-viral and 60 cases of cirrhosis of mixed etiology. All the data thus obtained was arranged in a tabulated form and analyzed using SPSS software. Percentage and frequency distribution were used to describe the results.
Results: The present study enrolled 120 subjects, out of these 80 were males and 40 were females. The mean age of the study population was 40.23+/- 7.89 years. Ductopenia was shown by single subject of liver cirrhosis. Blood stasis was observed by 3.3% liver cirrhosis and 1.7% hepatitis subjects. Focal type of necrosis was seen amongst 68.3% (n=41) liver cirrhosis subjects and 73.3% (n=44) hepatitis subjects. Inflammatory infiltrate was seen amongst 36.7% (n=22) liver cirrhosis subjects and 16.7% (n=10) chronic hepatitis subjects.
Conclusion: In present study; portal inflammation was most common mesenchymal change in liver cirrhosis and hepatitis. Focal type of necrosis was seen in both the cases.
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