A Prospective Study on Postmenopausal Type 2-Diabetic Women Suffering from Knee Osteoarthritis in a Tertiary Care Teaching Hospital
Background: Knee osteoarthritis is the most common form of joint disorder and a leading cause of pain and functional disability among elderly female population. Type 2-diabetes is frequently reported comorbidity in elderly female patients with knee osteoarthritis. Therefore, the aim of this study is to assess the role of various blood biochemical parameters in cases of knee osteoarthritis among type 2 diabetic postmenopausal women. Methods: The present study conducted in the Department of Orthopaedics, Pacific Medical College and Hospital, Udaipur, Rajasthan. 55 type 2-diabetic female subjects of age above 50 years were enrolled as cases and 55 normal healthy female age matched individuals as controls. Osteoarthritis of knee was ascertained using the American college of rheumatology classification criteria. Results: The mean levels of fasting blood sugar, HbA1c, total cholesterol, TG, LDL-C and VLDL-C were also found significantly increased while HDL-C was found significantly decreased in cases as compared to controls. Conclusions: We concluded that there is a positive correlation with increased levels of HbA1c and FBS (p˂0.001) in diabetic postmenopausal women and knee osteoarthritis.
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