A Tertiary Care Hospital Based Study on Prevalence of Metabolic Syndrome in Coronary Artery Disease Cases

  • Satish Chandra Arya Assistant Professor, Dept. of General Medicine, K M Medical College & Hospital, Mathura, U.P, India.
  • Rajendra Prasad Gupta Assistant Professor, Dept. of General Medicine, K M Medical College & Hospital, Mathura, U.P, India.
Keywords: Metabolic syndrome, IHD, cardio metabolic risk factors


Background: Coronary artery disease (CAD) is the major causes of death in the developed world. It has been reported that there is high prevalence of cardiac risk factors and associated morbidity in the adult population. These risk factors are known as the metabolic syndrome. Due to the alterations in lifestyle, low physical activity, the epidemic of obesity and insulin resistance, metabolic syndrome is a growing health problem in adults.

Methods: In this study, 150 total numbers of cases were included. This study conducted in the Department of Medicine in K M Medical College & Hospital, Mathura. The duration of study was over period of one year.

Results: In this study, 150 total numbers of cases were included. Out of  150 cases 65.4% were male and 34.6% were female.36% cases 51-60 age group predominantly found followed by >60 & <51.  This study showed risk factor of Diabetic mellitus which were in 67 cases in IHD with metabolic syndrome group. While in IHD without metabolic syndrome group IHD higher risk found followed by other group.

Conclusions: This study suggested that, Metabolic syndrome significantly increases the risk of coronary artery disease also. To prevent the development of metabolic syndrome, it is necessary to modify lifestyle.


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1. Grundy SM. Metabolic Syndrome: Connecting and Reconciling Cardiovascular and Diabetes Worlds. J Am Coll Cardiol 2006;47 :1093-100.
2. Mohan V, Rao GHR. Type 2 Diabetes in South Asains. 1st ed. New Delhi: South Asian Society on Atherosclerosis and Thrombosis; 2007.
3. Prasad DS, Kabir Z, Dash AK, Das BC. Abdominal obesity, an independent cardiovascular risk factor in Indian subcontinent: A clinico epidemiological evidence summary. J Cardiovasc Dis Res 2011;2: 199-205.
4. Fiuza M. [Metabolic syndrome and coronary artery disease] Rev Port Cardiol. 2012;31(12):779–782.doi: 10.1016/j.repce.2012.10.004. [PubMed] [CrossRef] [Google Scholar]
5. Hajian-Tilaki K. Metabolic syndrome and its associated risk factors in Iranian adults: A systematic review. Caspian J Intern Med. 2015;6(2):51–61. [PMC free article] [PubMed] [Google Scholar]
6. Azizi F, Hadaegh F, Khalili D, Esteghamati A, Hosseinpanah F, Delavari A, Larijani B. et al. Appropriate definition of metabolic syndrome among Iranian adults: report of the Iranian National Committee of Obesity. Arch Iran Med. 2010;13(5):426–428. [PubMed] [Google Scholar]
7. Veghari GH, Sedaghat M, Banihashem S, Moharloei P, Angizeh A, Tazik E. et al. The Prevalence of Metabolic Syndrome in the North of Iran. An Epidemiologic Comparative Study. J Cardiovasc Disease Res. 2015;6(4):172–175. doi: 10.5530/jcdr.2015.4.1. [CrossRef] [Google Scholar]
8. Neeb ZP, Edwards JM, Alloosh M, Long X, Mokelke EA, Sturek M. Metabolic syndrome and coronary artery disease in Ossabaw compared with Yucatan swine. Comp Med. 2010;60(4):300–315. [PMC free article] [PubMed] [Google Scholar]
9. Zidi W, Allal-Elasmi M, Zayani Y, Zaroui A, Guizani I, Feki M, Mourali MS. et al. Metabolic Syndrome, Independent Predictor for Coronary Artery Disease. Clin Lab. 2015;61(10):1545–1552. [PubMed] [Google Scholar]
10. Anand Verma, Abhishek Agarwal et al. Association between Metabolic Syndrome andcAcute Coronary Syndrome in Central India. Sch. Acad. J. Biosci., 2016; 4(3A):218-223.
11. Ana Jover, Emili Corbella et al. Prevalence of Metabolic Syndrome and its Componentscin Patients with Acute Coronary Syndrome. Rev Esp Cardiol. 2011; 64(7):579–586.
12. R.Gupta, VP Gupta, M Serna, H Prakash, Shweta Rastogi. Serial epidemiologicalcsurveys in urban Indian population demonstrate increasing coronary risk factor amongcthe lower socioeconomic strata. JAPI. 2003:51:470 -7.
13. Pankaj Shah. Metabolic syndrome. Mechanism and measurement of insulin resistance.Metabolic syndrome proceeding of the VIIth Annual Ranbaxy science foundation symposium. Dec 23 -2003.
14. Bonora E, Targher G et al. The Metabolic Syndrome is an independent predictor of cardiovascular disease in Type 2 diabetic subjects. Prospective data from the Verona Diabetes Complications Study. Diabet Med 2004;21:52-8.
15. Santosh Kumar Sinhaa, Amit Goela et al. Prevalence of Metabolic Syndrome and Its Clinical and Angiographic Profile in Patients with Naive Acute Coronary Syndrome in North Indian Population. J Clin Med Res. 2016;8(9):667-673.
16. Mohammad Ali Sowdagar, AN Otikunta et al. A Study of the Cardiovascular Risk Factor Profile in Patients with Acute Coronary Syndrome with Particular Reference to Metabolic Syndrome. International Journal of Clinical Medicine. 2015: 6: 859-866.
17. Ajay Rajbhandari, Dipendra Raj Pandeya et al. Prevalence of Metabolic Syndrome and its Component in Patients with Acute Coronary Syndrome. MJSBH. July-December 2013: Vol 12: Issue 2.
18. Kim JY, Mun HS, Lee BK et al. Impact of metabolic syndrome and its individual components on the presence and severity of angiographic coronary artery disease. Yonsei Med J 2010; 51: 676-82.
How to Cite
Arya SC, Gupta RP. A Tertiary Care Hospital Based Study on Prevalence of Metabolic Syndrome in Coronary Artery Disease Cases. Int Arch BioMed Clin Res [Internet]. 2019Jun.30 [cited 2020Jul.6];5(2):42-4. Available from: https://iabcr.org/index.php/iabcr/article/view/517
ORIGINAL ARTICLES ~ General Medicine