A Dental Surgeon’s Experience in A Biotechnology Lab: Trying to Resolve Surgical Controversies with Blood-Derived Growth Factors

  • Carlos Fernando de Almeida Barros Mourão Department of Oral Surgery, Dentistry School, Fluminense Federal University, Niterói, Rio de Janeiro - Brazil.
Keywords: Dental Experience, Blood Derived Growth Factors, Surgical Controversies

Abstract

Nowadays, there are a lot of articles about blood-derived growth factors (BDGF) using different protocols. These blood by-products have many applications in Medicine, especially in Dentistry. The most important thing is the use of an autologous biomaterial, from the patient's own blood to improve healing, soft tissue growth, hemostasis etc.[1-5] Many dental surgeons use BDGF in their surgical protocols, which is possible to observe in scientific articles,[1-4] dentistry congresses and especially on social media (although the last is unethical way to share and publish research results or cases reports).

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References

Lourenço ES, Mourão CFAB, Leite PEC, Granjeiro JM, Calasans-Maia MD, Alves GG. The in vitro release of cytokines and growth factors from fibrin membranes produced through horizontal centrifugation. J Biomed Mater Res A. 2018 ; 106(5):1373-1380
2. de Almeida Barros Mourão CF, Calasans-Maia MD, de Mello Machado RC, de Brito Resende RF, Alves GG. The use of platelet-rich fibrin as a hemostatic material in oral soft tissues. Oral Maxillofac Surg. 2018; 22(3):329-333
3. De Andrade LS, Leite LP, De Melo Silva FB, De Brito Resende RF, Guedes De Uzeda MJ. The use of platelet-rich fibrin concentrates in tissue healing and regeneration in dentistry. Int J Growth Factors Stem Cells Dent 2018;1: 23-6.
4. de Almeida Barros Mourão CF, Lourenço ES, Nascimento JRB, Machado RCM, Rossi AM, Leite PEC, Granjeiro JM, Alves GG, Calasans-Maia MD. Does the association of blood-derived growth factors to nanostructured carbonated hydroxyapatite contributes to the maxillary sinus floor elevation? A randomized clinical trial. Clin Oral Investig. 2018 doi: 10.1007/s00784-018-2445-7. [Epub ahead of print]
5. Forabosco A, Gheno E, Spinato S, Garuti G, Forabosco E, Consolo U. Concentrated growth factors in maxillary sinus floor augmentation: A preliminary clinical comparative evaluation. Int J Growth Factors Stem Cells Dent 2018;1:2-7.
6. Barros Mourão CF, Gheno E, Lourenço ES, Barbosa Rd, Kurtzman GM, Javid K, et al. Characterization of a new membrane from concentrated growth factors associated with denaturized Albumin (Alb- CGF) for clinical applications: A preliminary study. Int J Growth Factors Stem Cells Dent 2018;1:64-9.
Published
2018-12-29
How to Cite
1.
MourãoCF. A Dental Surgeon’s Experience in A Biotechnology Lab: Trying to Resolve Surgical Controversies with Blood-Derived Growth Factors. IABCR [Internet]. 29Dec.2018 [cited 23Jan.2019];4(4):1-. Available from: https://iabcr.org/index.php/iabcr/article/view/426