Study of Acute Kidney Injury Associated with Pregnancy
Background: Pregnancy related acute kidney injury(PRAKI) is common in developing countries like India. The aim of the study was to identify the etiology, prognosis, management and to have preventable measures, to improve the maternal and fetal outcome.
Methods: The study was conducted in S.P. Medical College& Hospital – Obstetrics and Gynecology Department from July 2017 to December 2017.A total of 22 cases has been studied.
Results: The incidence of PRAKI was 1.3% in our hospital. Pregnancy induced hypertension, pre-eclampsia, eclampsia was found to be commonest cause. Incidence of PRAKI was high in third trimester. The outcome was favorable with complete recovery in 45.47% patients.
Conclusion: The low incidence of PRAKI was probably due to improved obstetric practices. Future research is further needed, to decrease the incidence.
2. 2.Dunlop Davidson JM. Renal hemodynamics and tubular function in human pregnancy. Baillie's Clinical Obstetric Gynaecol.1987;1(4):769-87.
3. 3.Walker JJ. Pre-eclampsia. Lancet 2000; 356:1260-5 [PubMed]
4. 4.Prakash J, Pandey LK, Singh AK, Kar B, Hypertension in pregnancy Hospital based study. J Association of Physicians of India 2006; 54:273-8 [PubMed]
5. 5.M.B. Beaufils, Pregnancy, in clinical nephrology, A.M. Davidson, J.S. Cameron, G.p. Grunfield et al, Eds PP 1704-1728, Oxford University Press, New York, NY USA,3rd edition,2005.
6. 6.Kurzel RB. Serum magnesium levels in pregnancy and preterm labor. Am J Perinatol,1991;8(2):119-27.
7. 7.M.R. Ansari, M.S. Laghari and K. BSolangai, Acute renal failure in pregnancy: One year observational study at Liaquat university Hospital, Hyderabad, Journal of Pakistan medical association, vol.58, no.2, pp. 61-64,2008.
8. 8.V. Sivakumar, Ramakrishna, and V.V. Sai Naresh, “Pregnancy related acute renal failure: a 10-year experience, “Saudi Journal of Kidney Diseases and Transplantation, vol .22, no.2, pp.352-353,2011.
9. 9.Najar MS, Shah AR, Banday KA, Bhat MA et al, Pregnancy related acute Kidney Injury: A single center experience from Kashmir Valley, Indian Journal,2008:18(4):159 -61.
10. M.A. Khalil, A. Azhar, N. Anwar, A. Amin Ulla, Najm -ud-din and R. Walli,” Etiology, Maternal and Fetal outcome in 60 cases in obstetric acute renal failure. Journal of Aubyn Medical College., Vole 21, no.4pp.46-49,2009.
11. P.U. Rani and G. Narayen, Anuradha”, Changing trends in pregnancy related acute renal failure,” Journal of Obstetrics and Gynecology of India, vol.52, pp.36-38,2002.
12. Kilari SK, Chitra RK, Vishnubhotla SK. Pregnancy related Acute Renal Failure. Journal of Obstetrics and Gynaecol. Of India.2006;56.308 -10.
13. M. Erdemoglu, U. Kuyumcuoglu, A. Kale and N. Akdeniz,” Pregnancy related acute renal failure in Southeast region of Turkey: analysis of 75 cases s Clinical and Experimental Obstetrics and Gynecology, vol.37, no.2. pp.148-149,2000.
14. N. Arora, K. Mahajan, N. Jana, and Taraphder,” Pregnancy related acute renal failure in eastern India,” International Journal of Gynecology and Obstetrics” vol 111, no.3, pp.213-216,2010.
15. K.R. Gopalini, P.R. Shah, D.N. Gera et al, “Pregnancy -related acute renal failure: a single center experience, “Indian Journal of Nephrology, vol ,18. no.1.pp17-21,2008.
16. N. Chaudri, G.U. But. I, Masroor et al,” Spectrum and short-term outcome of pregnancy related acute renal failure among women, “Annals of Pakistan Institute of Medical Sciences, vol.7, no.2, pp.57-61,2011.
17. Prakash Tripathi Malhotra Kumar Srivastava. Acute renal failure in eastern India. Nephrol Dial Transplant.1995;10.2009-12[PubMed]