Use of Anti Angiogenic Drug in the Treatment for Age Related Macular Degeneration

  • Wg Cdr Sapna Raina 1Assistant Professor; Classified Specialist Ophthalmology, Air Force Central Medical Establishment (AFCME), New Delhi, India
  • Bhupinder Kaur Anand Professor, Department of Community Medicine, SGT Medical University, Gurugram, Haryana, India.
  • Marwaha Manvinder Pal Singh Classified Specialist Aerospace Medicine, Air Force Central Medical Establishment (AFCME), New Delhi, India.
  • Professor (Maj Gen) JKS Parihaar Senior Consultant, Department of Ophthalmology, Center of Sight, New Delhi, India
Keywords: Angiogenic drug, Macular degeneration, Eye OPD, IVB, Bevacizumab


Background: Age-related macular degeneration (AMD) is the leading cause of irreversible blindness. Currently 2.5-3 million people worldwide are blind due to AMD.

Objective:- This study were to  use of anti-angiogenic drug in the treatment for age related macular degeneration.

Methods: A cross sectional study was carried out among patients attending Eye OPD of a tertiary care eye center.

Results: 25 patients were included in this study . Among the 25 patients 15 were male & 10 were female. Mean visual acuity (VA) in this study improved from 5/60 to 6/36 during follow up. This was statistically significant (P <0.0001).

Conclusion: The results of this study suggest that IVB (1.25 mg) is well tolerated and associated with stabilization or improvement in visual acuity, decreased central macular thickness (CMT) by ocular coherence tomography (OCT), and reduction in angiographic leakage associated with neovascular AMD.


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How to Cite
Raina WCS, Anand BK, Singh MMP, Parihaar P (Maj GJ. Use of Anti Angiogenic Drug in the Treatment for Age Related Macular Degeneration. Int Arch BioMed Clin Res [Internet]. 2018Jun.28 [cited 2021Jun.16];4(2):158-61. Available from: