A Correlation of Cerebral Malaria with Different Changes in Hepatitis: A Hospital Based Study
Background: Ventilator associated pneumonia (VAP) is a type of nosocomial pneumonia occurring in patients who are mechanically ventilated for more than 48 hours. VAP is the most common nosocomial infection occurring in the intensive care units and its incidence varies from 8% to 28%.
AIMS & OBJECTIVES- This study was done to determine the bacteriological profile and antibiotic sensitivity pattern of the isolates obtained from the endotracheal aspirates of the clinically suspected patients of VAP in ICU. Materials & Methods: The study was conducted in the department of general medicine of the Haridev Joshi Hospital, Dungarpur, Rajasthan, India. The present study included 52 patients who had serum bilirubin > 3 mg%. So, after excluded patient the study group included 45 patients. All patients were underwent a set of investigations, including conjugated and unconjugated bilirubin, and serum AST and ALT levels. All the patients with cerebral malaria underwent detailed ultrasonography to check the size and echo-texture of the liver. Results: A total of 45 patients with malaria were included in the study. The mean serum bilirubin level was 11.23+6.8 mg %, mean AST levels was 298.42+242.21 IU/l and mean ALT levels was 382.21+298.12 IU/l. 17 patients were diagnosed having cerebral malaria. The patients with cerebral malaria were directed to undergo USG abdomen. Enlarged size if liver was seen 14 patients. Conclusion: Within the limitations of our study we conclude that significant hepatitis findings are seen in patients with cerebral malaria. Required supportive and anti-malarial treatment should be provided to the patients with specially taking care of the hepatic health.
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