Role of Vitamin D in Prediabetic Individuals – Update

  • Vishal Prakash Giri Department of Pharmacology, TMMC&RC, Moradabad.
  • Om Prakash Giri Department of Pulmonary medicine, DMCH, Darbhanga
Keywords: Deficiency, Prediabetes, Vitamin D


Vitamin D deficiency and diabetes have one common trait of being pandemic. Association between insulin sensitivity and serum 25-OHD levels is clear. Patients with diabetes and Vitamin D deficiency have increased insulin resistance. Vitamin D supplementation may decrease the incidence of diabetes mellitus and may improve the metabolic control in the diabetes state


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1. Al Mheid I, Patel RS, Tangpricha V, Quyyumi AA. Vitamin D and cardiovascular disease: is the evidence solid? Eur Heart J. 2013 [Epub ahead of print].
2. Gepner AD, Ramamurthy R, Krueger DC, Korcarz CE, Binkley N, Stein JH. A prospective randomized controlled trial of the effects of vitamin D supplementation on cardiovascular disease risk. PLoS One. 2012;7(5):e36617.
3. Barengolts E. vitamin D role and use in prediabetes. Endocr Pract.2010;16(3):476-85.
4. Giri VP, Shubhra K, Giri OP, Haque A. Prescription Audit of Acne Vulgaris in Skin Outpatient Department of a Tertiary Care Teaching Hospital. Journal of Evolution of Medical and Dental Sciences 2014;3(52):12179-12183. DOI: 10.14260/jemds/2014/3607
5. Goswami R, Mishra SK , Kochupillai N. Prevalence & potential significance of vitamin D deficiency in Asian Indians., Indian J Med Res. 2008;127:229-238.
6. Preventing the progression of pre-diabetes to type 2 diabetes in adults. Available at http// Accessed on 22.6.13.
7. Knekt P, Laaksonen M, Mattila C, et al. Serum vitamin D and subsequent occurrence of type 2 diabetes. Epidemiology. 2008;19(5):666-71.
8. Norman AW, Frankel JB, Heldt AM, et al. Vitamin D deficiency inhibits pancreatic secretion of insulin. Science. 1980;209(4458):823-5.
9. Kayaniyil S, Vieth R, Retnakaran R, et al. Association of vitamin D with insulin resistance and beta cell dysfunction in subjects at risk for type 2 diabetes. Diabetes care. 2010;33(6):1379-81.
10. Griz LH, Bandeira F, Gabbay MA, Dib SA, Carvalho EF. Vitamin D and diabetes mellitus: an update 2013. Arquivos Brasileiros de Endocrinologia & Metabologia. 2014;58(1):1-8.
11. Talaei A, Mohamadi M, Adgi Z. The effect of vitamin D on insulin resistance in patients with type 2 diabetes. Diabetol Metab Syndr. 2013;5(1):8.
12. Lee JH, O’keefe JH, Bell D et al. Vitamin D deficiency an important, common, and easily treatable cardiovascular risk factor? J Am Coll Cardiol. 2008;52(24):1949-56.
13. Mathieu C, Gysemans C, Giulietti A, et al. Vitamin D and diabetes. Diabetologia. 2005;48(7):1247-57.
14. Shankar A, Sabanayagam C, Kalidindi S, et al. Serum 25-Hydroxyvitamin D Levels and prediabetes Among subjects free of Diabetes. Diabetes care. 2011;34(5):1114-1119.
15. Deleskog A, Hilding A, Brismar K, et al .low serum 25-Hydroxyvitamin D level predicts progression to type 2 diabetes in individuals with prediabetes but not with normal glucose tolerance. Diabetologia.2012;55(6):1668-78.
How to Cite
Giri VP, Giri OP. Role of Vitamin D in Prediabetic Individuals – Update. Int Arch BioMed Clin Res [Internet]. 2015Dec.25 [cited 2019Nov.14];1(2):33-5. Available from: