Assessment on Anesthetic Requirement and Peri-operative Hemodynamic Stress Response after a Single Pre-operative Dose of Dexmedotomidine Versus Fentanyl: A Hospital Based Study


  • Vinod Rathore Assistant Professor, Department of Anaesthesiology, Rohilkhand Medical College Author
  • Devendra Singh Assistant Professor, Department of Anaesthesiology, Rohilkhand Medical College Author



Dexmedetomidine, hemodynamic stress response, fentanyl


Background: Dexmedetomidine is an imidazole derivative and highly specific and selective α-2 adrenergic receptor agonist. The time of endotracheal intubation, extubation and laparoscopy are the most crucial times which may provoke and aggravate transient, but severe sympathetic responses such as tachycardia and hypertension.

Methods: Total 99 cases were included in this study. This study had two groups. In group 1 50 cases were included and in group 2 49 cases were included. This study was conducted in Department of Anesthesia.

Results: Total 99 numbers of cases were included in this study. Total cases were split in to two groups. Group 1 had 50 cases & group 2 had 49 cases. Adverse effect found in this study that was bradycardia in 1 case of group 1.

Conclusions: This study concludes that by providing smooth recovery without undue sedation with better analgesia Dexmedetomidine reduces the need of analgesics in comparison to Fentanyl.


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