Use of Antihypertensive Drugs in Type 2 Diabetic Patients - A Hospital Based Study in Rajsamand
Introduction: Diabetes Mellitus has been closely associated with Hypertension. Hypertension is major risk factor for development of diabetes as well for complications like nephropathy, CAD and neuropathy etc. Therefore, controlling Hypertension is vital to prevent and retard progression of microvascular and macrovascular complications. Therefore, we undertook this study to evaluate treatment patterns in diabetic patients with hypertension, those are being followed at our institute.
Materials and Methods: This study was conducted on diabetic patients who had hypertension as well attending Medicine department of Ananta Institute of Medical Sciences & Research Center, Rajsamand, Rajasthan. Antihypertensive drugs were analysed on all diabetic patients reporting to medicine OPD from February 2016 to April 2016 at our institute were screened.
Results: Around 145 patients were included in our study. Out of 145 patients, only n=112 patients completed our study. Out of n=112 patients, 62 were males and 50 were females. Mean age of group was 52.5 years. N=33 patients were on monotherapy and remaining patients were on combination antihypertensive drugs. There were total 331 antihypertensive drug exposures. Angiotensin receptor blockers were the most commonly prescribed drugs. Angiotensin inhibitors (angiotensin receptor blockers and ACE inhibitors) were utilized in n=150 patients.
Conclusion: Our study showed that majority of diabetic hypertensive patients needed multiple drug therapy to control hypertension. Most of the patients were on ARBs/ACE inhibitors. This was according to recommendation by ADA or JNC8.
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