A Prospective Study on Platelet Counts – APrognostic Marker to Predict the Feto-Maternal Outcome in Pre-eclampsia and Eclampsia

  • Sanchita Dashora Assistant Professor, , Department of Obstetrics and Gynaecology, Pacific Medical College and Hospital, Udaipur.
  • Rajrani Sharma Senior Professor & Head, Department of Obstetrics and Gynaecology, Pacific Medical College and Hospital, Udaipur.
Keywords: Platelets, pre-eclampsia, eclampsia

Abstract

Background: Hypertensive disorders represent the most common medical complication of pregnancy affecting 7-15 % of all gestations and a leading cause of maternal and fetal morbidity and mortality especially in cases of pre-eclampsia and eclampsia. Out of all the haematological changes that occur in pre-eclampsia and eclampsia, thrombocytopenia is the most common haematological abnormality. Assessment of platelet count is a simple, cheap and relatively sensitive method to know the prognosis and to predict the feto-maternal outcome in pregnancy complicated by pre-eclampsia and eclampsia. Methods:This was a prospective study conducted in the Department of Obstetrics and Gynaecology, Pacific Medical College and Hospital, Udaipur over a period of 1 year which included 50 cases of pre-eclampsia and eclampsia and 50 cases of normotension in 3rd trimester of pregnancy. Results: Total 50 cases of pre-eclampsia and eclampsia were studied. Platelet count was significantly reduced with the severity of pre-eclampsia and eclampsia and it reflects feto-maternal outcome. Conclusions:Estimation of platelet count can be a reliable, rapid, easy and cheap method for early detection and assessment of severity at earlier gestational age which can help us to improve fetomaternal outcome.

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References

1. American College of Obstetricians & Gynaecologists. Diagnosis and Management of Pre-Eclampsia and Eclampsia. Practice Bulletin No. 33. Washington, DC, January 2002.
2. NHBPEP (National High Blood Pressure Education Program) Working Group on High Blood Pressure. Report of the National High Blood Pressure Education Program Working Group in High Blood Pressure in Pregnancy. Am J Obstet Gynecol. 2000; S1-22.
3. James PR, Nelson-Piercy C. Management of Hypertension before, during, and after pregnancy. Heart. 2004; 90:1499-1504.
4. Baha M Sibai. Hypertension in pregnancy. In: S.G. Gabbe, J.R. Niebyl, J.L. Simpson editors. Obst. Normal and Problem of Pregnancies. 3rd Edn, New York: Churchill Livingstone; 1996; p. 935-991.
5. Walker JJ, Cameron AD, et al Am J Obstet Gynaecol 161: 676-679, 1989
6. Practical Guide to High Risk Pregnancy and Delivery, 3rd Edition by Fernando Arias, MD, PhD, Amarnath G Bhide, Arulkumaran S, KaizadDamania, Shirish N Daftary.
7. Giles C, Inglis TC. J Obstet gynaecol Ind 88: 1115-1159, 1981.
8. Vigil D, Gracia U. Pregnancy complicated by pre-eclampsia, eclampsia with HELLP syndrome P. International Journal of Gynaecology & Obstetrics 2001; 72: 17-23
9. Vamsheedhar Annam, Srinivas K, Yatnatti SK, Suresh DR. Evaluation of platelet indices and platelet counts and their significance in preeclampsia and eclampsia. Int J Biol Med Res 2011; 2:425-28.
10. Prakash J, Pandey LK, Singh AK, Kar B. Hypertension in pregnancy: Hospital based study. J Assoc Physicians India 2006; 54:273-8.
11. Kulkarni RD, Sutaria UD. Platelet counts in toxemia of pregnancy. J Obst Gynaecol Ind 1983; 33: 321-325.
12. Joshi kale, Vrunda, Sapre shaila. J Obstet Gynecol Ind Vol 54, No. 3; May/June 2004 page 235-236
13. Mohapatra S, Pradhan BB, Satpathy UK, Mohanty A, Pattnaik JR. Platelet estimation: Prognostic values in pregnancy induced hypertension. Indian J physiolpharmacol 2007; 51:160-64.
14. Dr Ellora Devi; Combination of Platelet & Uric Acid Estimation Can Predict Severity of Pih Better; Int J Pharm Bio Sci 2012 July; 3(3): (B) 1039 - 1045
15. Kumar Majhi, Sorathy Chakravorty, (2000) Calcutta; (Eclampsia present scenario in medical college, Calcutta) Obstet. Gynecol India, 2000; 50:128-32
16. Sibai MD, Mark M, Taslimi, Am J Obstet Gynecol Vol 155, issue 3, Sep 1986, Pg 501-507.
Published
2017-12-20
How to Cite
1.
Dashora S, Sharma R. A Prospective Study on Platelet Counts – APrognostic Marker to Predict the Feto-Maternal Outcome in Pre-eclampsia and Eclampsia. International Archives of BioMedical and Clinical Research [Internet]. 20Dec.2017 [cited 22May2018];3(4):37-0. Available from: https://iabcr.org/index.php/iabcr/article/view/14