Correlation of Morphological Findings with Hormonal Levels in Normal and Poly Cystic Ovary Syndrome Patients

Authors

  • Motwani Veena Assistant professor, Department of Anatomy, CIMS, Bilaspur Author
  • C. Banerjee ex Professor, Department of Anatomy, Pt. J. N. M. Medical College, Raipur(C.G.) Author

DOI:

https://doi.org/10.21276/pw7ccn49

Keywords:

PCOD, Hormone Levels

Abstract

Background: The PCOS is the commonest endocrinal disturbance leading to infertility and oligomenorrhea characterized by the presence of enlarged ovaries with multiple small cysts and a hypervascularized androgen secreting stroma.

Materials and methods: Total 105 cases between the age 18 to 40 years were studied, out of which 25 were normal to serve as control and 80 PCOS patients were selected. Size and Volume of both ovaries was measured by USG. Hormonal levels for serum LH, FSH, and LH : FSH ratio were determined by chemiluminescence method {CLIA}.

Results: So most of the patient were in age group 21 to 30 yrs i.e. 15 patients (60%). So mean ovarian volume was within normal range (less than 10cc) in all the age groups.

Conclusion: In our study LH:FSH ratio was found more than 2 in 51.25% of PCOS patients and USG positive morphological findings of ovaries were found in all the 80 patients of PCOS (100%). There is a significant co-relation between ovarian morphology and LH: FSH Ratio.

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References

Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, et al. (2004) Нe prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 89: 2745-2749.

Zawadski JK, Dunaif A (1992) Diagnostic criteria for polycystic ovary syndrome: towards a rational approach. In: Dunaif A, Givens JR, Haseltine FP, Merriam GR (eds.) Polycystic ovary syndrome, Blackwell 6cLentLٽc Publications, Boston, MA, pp: 377-384.

Нe Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group (2004) Revised 2003 consensus on the diagnostic criteria and long term health risks related to polycystic ovary syndrome. Fertil Steril 81: 19-25.

Azziz R (2006) Controversy in clinical endocrinology: diagnosis of polycystic ovarian syndrome: the Rotterdam criteria are premature. J Clin Endocrinol Metab 91: 781-785.

Welt CK, Gudmundsson JA, Arason G, Adams J, Palsdottir H, et al. (2006) Characterizing dLوٴerent subsets of polycystic ovary syndrome as deٽned by the Rotterdam criteria: Нe impact of weight on phenotype and metabolic features. J Clin Endocrinol Metab 91: 4842-4848.

Dunaif A (1997) Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocr Rev 18: 774-800.

Panidis D, Tziomalos K, Macut D, Delkos D, Betsas G, et al. (2012) Crosssectional analysis of the eوٴects of age on the hormonal, metabolic, and ultrasonographic features and the prevalence of the dLوٴerent phenotypes of polycystic ovary syndrome. Fertil Steril 97: 494-500.

AA. Kyei, Mensah, Slin Tan, J. Zaidi, HS Jacobs, 1998, Morphology of ovary in PCOS patients, Human Reproduction, vol.13, 1437-1441

Hongning Xie, Hiroko Kurioka, Kohkichi Hata, Atsushi Manabe, Kentaro Tukahashi, Kohji Miyazaki, 2001, Correlation of ovarian volume in PCOS patients, Journal of M. USG, vol. 28 No.1, 7-10.

Fouzia Nazir, Shagufta S,Mariam M, Huma A, Saddal A, Saad R., 2008, Polycystic ovrian syndrome-management in fertility deprivtion. Pak J Obstet Gynaecol; 12(1-2):59-71.

De Vane GW, Czekala NM, Judd Hl, Yen SSC, 1975, Circulating gonadotropins, estrogens and androgens in polycystic ovarian disease. American Journal of obstetrics and Gynaecology ; 121:496-500.

Bhattacharya D., Mandal Salil K., Mukherjee S. Pradhan M. 2004– Clinical correlation with biochemical status in PCOS patients, The Journal of Obstetricsand Gynecology of India, Vol. 55, No.1 : 67-71

Li Wei Cho, Jayagopal Vijay, Kilpatrick Eric S., Holding Stephen, Atkin Stephen L, 2006 Role of LH and FSH ratio in diag. PCOS, Annals of Clinical Biochemistry, Vol.43: 217-213.

Balen AH, Conway GS, Kaltas G, Techatrasak K, Manning PJ, West C., 1995, Polycystic ovary syndrome: The spectrum of the disorder in 1741 patients. Hum Reprod; 10:2107-11

BN Chakravarty and Yashwant Mane, 2006, Metabolic and Endocrine changes during Normal Puberty and their relevance to Adolscent PCOS, Polycystic Ovary Syndrom An update (Jaypee Publication), 1st edition, 66-81.

Adams J, Poloson BW, Franks S, 1985, Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism, Br. Med. J. (Clin Res Ed) Aug; 293 (6543) : 355-9

Published

12.03.2024

Issue

Section

ORIGINAL ARTICLES ~ Human Anatomy

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