Single Dose Extradural Analgesia Vs Bupivacaine and Lignocaine with Adrenaline: A Comparative Hospital Based Study in Solan

  • Mandeep Goma Assistant Professor, Department of Anaesthesiology, Maharishi Markandeshwar Medical College & Hospital, Solan, H.P
Keywords: Analgesia, Bupivacaine, Clonidine.


Background: Lignocaine and bupivacaine are mainly used local anaesthetics in the present day. Therefore, we are presenting a comparative study of single dose extradural analgesia with Bupivacaine and Lignocaine with adrenaline.

Methods: The study was carried out in 30 healthy subjects posted for lower abdominal, pelvic, perineal and lower limb surgeries. They were randomly divided into 2 groups. Group I and Group II. Group I (N=15): Received 20ml of 1.5% Lignocaine with adrenaline 1:200000. Group II (N=15): Received 20ml of 0.5% Bupivacaine.

Results: The mean times (with standard times) been extradural injection and onset of analgesia indicate that Lignocaine had a significantly quicker onset of action. Intra operative complications like hypotension, drowsiness, nausea and vomiting and post-operative complications like headache, back ache, nausea, vomiting, retention of urine and neurological sequelae were noted.

Conclusion: Lignocaine with adrenaline had a significantly quicker onset of action. Duration of analgesia produced by Bupivacaine was found to be significantly longer than that produced by Lignocaine with adrenaline.


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How to Cite
Goma M. Single Dose Extradural Analgesia Vs Bupivacaine and Lignocaine with Adrenaline: A Comparative Hospital Based Study in Solan. Int Arch BioMed Clin Res [Internet]. 2018Feb.4 [cited 2023Sep.25];3(1):88-1. Available from: