A Study to Record the Changes in Blood Pressure and Blood Glucose Levels on Vitamin C and E Supplementation in Urban Population
DOI:
https://doi.org/10.21276/55he5p82Keywords:
Diabetes, Lipid Profile, Vitamin C & EAbstract
Background:Antioxidants are chemical compounds that giving an electron to free radical molecules convert them to a harmless configuration, avoiding damaging chain reaction, which involve lipids, proteins enzymes carbohydrates, DNA, cell and nuclear membranes lead to cell death. Either exogenous or endogenous they are addressed to prevent the oxidation induced damage, a process that causes damage in all tissues through free radicals chemical reactivity. Our aim was defining the state of the art of antioxidant therapy, with specific reference on the evidence based clinical use of Vitamin C & E in diabetic, hypertensive& nutritional anemic patients in rural population.
Methods: It is an interventional study done on 420 patients. These were divided in six groups each 70 patients both control & test in rural population which is of low density. Control group comprises of diabetic, anemic & anemic patients on treatment without supplementation & test group of 70 patients with supplementation. Both groups received treatment for 12 weeks.
Results: Combined doses of both vitamins showed improvement in hemoglobulin; however post prandial blood sugar & HbA1c levels in type 2 diabetics showed moderate glycaemia control.
Conclusion: Patients with diabetes, heart diseases &anaemia showed marked improvement in various parameters with supplementation of antioxidants with therapy.
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References
Craig Weber M.D. High Blood Pressure. About.com: Newsletter. July 23,2009
Rolo AP, Palmeira CM. Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress. Toxicol Appl Pharmacol. 2006; 212: 167–78.
Ghafoorunissa; Krishnaswamy, K: Diet and coronary heart disease, ICMR, NIN Publicaton. 1985; 1-19.
Johnson-Wimbley TD, Graham DY. Diagnosis and management of iron deficiency anemia in the 21st century. Therapy Adv Gastroenterol. 2011;4:177–84.
World Health Organization. Anemia. 2018 May 21.
World Health Organization: The Global Prevalence of Anemia in 2011.
Alemayehu A, Gedefaw L, Yemane T, Asres Y. Prevalence, severity, and determinant factors of anemia among pregnant women in South Sudanese refugees, Pugnido, Western Ethiopia. Anemia. 2016; 2016: 9817358.
Bano S. Anemia in pregnancy. Indep Rev. 2015;17:53–9.
Haider BA, Olofin I, Wang M, Spiegelman D, Ezzati M, Fawzi WW, et al. Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: Systematic review and meta analysis. BMJ. 2013;346:f3443.
Bhimrao NJ. A critical review on iron deficiency anemia in female population of developing India. International Journal of Fauna and Biological Studies. 2016;3:116–9.
Bisoi S, Haldar D, Majumdar TK, Bhattacharya N, Sarkar GN, Ray SK. Correlates of anemia among pregnant women in a rural area of West Bengal. J FamWelf. 2011;57:72–8.
World Health Organization. Hemoglobin Concentrations for the Diagnosis of Anemia and Assessment of Severity. World Health Organization; 2011.
Halliwel B and Gutteridge JMC. Free radicals m biology and medicine, 3rd edition, Oxford University Press. U.K; 1999.
Parks E and traber MG, Mechanism of Vitamin E regulation; research over the past decade and focus on the future. Antioxid Redox signal. 2000; 2:405412.
Okoye ZSC. Biochemical functions of nutrients. In Biochemical aspects of nutrition, Prentice- Hall of India Private Ltd. New Delhi. 1992:51-1.
Okoduwa SIR, Umar AI, Ibrahim S, Bello F. Relationship of oxidative stress with type 2 diabetes and hypertension: Journal of Diabetiology. 2013;1:2.
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