Myocardial workload and fat oxidation in walking versus cycling by overweight and hypertensive adult males

  • Mayank Agarwal Autonomous State Medical College, Pratapgarh, Uttar Pradesh
Keywords: Exercise, Fat Oxidation, Myocardial oxygen demand, Respiratory Exchange Ratio, Rate Pressure Product


Background: The fast-paced increase in the prevalence of obesity and hypertension in India is burdening the country with non-communicable diseases that include cardiovascular disease. Exercise is a primary intervention to manage obesity and hypertension. Treadmill and stationary cycle are the most common form or modalities of indoor exercise adapted by individuals. The modality of exercise causing higher fat oxidation at a lesser myocardial workload should be preferred. The objective of the study was to compare the rate pressure product (RPP, a correlate of myocardial workload) and respiratory exchange ratio (RER, lower value indicates a higher contribution of fat oxidation to total energy expenditure during exercise) in treadmill walk with stationary cycling. Methods: The present crossover study involved twelve, overweight, hypertensive, and physically inactive adult males. The participants exercised for thirty minutes on the treadmill and stationary cycle with a target energy expenditure of 180 Kcal. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were recorded by an automated blood pressure monitor, and RPP in arbitrary unit (AU) was calculated as SBP×HR÷100. Respiratory gas exchange analysis determined the volume of oxygen consumed (VO2) and carbon dioxide produced (VCO2). RER was calculated as VCO2÷VO2. Student t-test was applied and P≤0.05 was considered significant. Results: SBP, HR, RPP, and RER was significantly higher in cycling (160.4±4.5 mmHg, 131.9±7.1 beats per minute, 211.4±8.6 AU, and 0.88±0.04) than the treadmill walk (158.4±4.9 mmHg, 129.6±7.6 beats per minute, 205.3±10.9 AU, and 0.86±0.03). Conclusion: Treadmill walk resulted in lesser myocardial workload and higher fat oxidation than cycling.


Download data is not yet available.
How to Cite
Agarwal M. Myocardial workload and fat oxidation in walking versus cycling by overweight and hypertensive adult males. Int Arch BioMed Clin Res [Internet]. 2021Oct.9 [cited 2022Jan.27];7(3):HP1-HP4. Available from:
ORIGINAL ARTICLES ~ Human Physiology