Quality of life among migraine patients: A cross-sectional questionnaire-based survey
DOI:
https://doi.org/10.21276/epvxt258Keywords:
Migraine, Headache, Chronic disease, quality of lifeAbstract
Background: Migraine is a chronic disorder which can negatively affects the quality of life of patients. So, we aimed to investigate the quality of life among migraine patients by conducting a questionnaire-based survey.
Materials and Methods: This was a cross-sectional questionnaire-based study which was conducted in the Department of Pharmacology in collaboration with Department of Medicine, ESIC Medical College and Hospital, Faridabad after prior approval from the Institutional Ethics Committee. The study period was of 6 months (Feb 2019–July 2019). 100 patients suffering from migraine were enrolled, out of which 97 agreed to participate in the study. For assessment of health related quality of life (HRQol) we used the validated Migraine disability assessment (MIDAS) score and Headache Impact Test (HIT-6) score.
Results: A total of 100 migraine patients completed the questionnaire. Majority of them belonged to 31-40 years of age. Seventy-seven percent of the participants were females, and almost half of the participants (54%) reported having family history of migraine. Sixty-six percent of the participants reported being diagnosed with migraine for >5 years, and 39% reported migraine attacks ranging from 1 to 4 times/month. The most common drug used for pain during migraine attack was paracetamol (acetaminophen) (78.4%) followed by stronger analgesics like ibuprofen, mefenamic acid, naproxen etc (49%); and tryptan derivatives (26%). The most used preventive medication was amitriptyline (49%) followed by propranolol (37%).
Conclusion: Chronic migraine has a negative impact on quality of life, predominantly in younger age of patients, patients with repeated episodes, those who are not using preventing medication and those suffering from chronic disease.
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References
Kvedar JC, Fogel AL, Elenko E, Zohar D. Digital medicine’s march on chronic
disease. Nature biotechnology. 2016;34(3):239.
Baksa D, Gonda X, Eszlari N, Petschner P, Acs V, Kalmar L et al. Financial
Stress Interacts With CLOCK Gene to Affect Migraine. Front BehavNeurosci.
;13:284.
AlHarbi FG, AlAteeq MA. Quality of life of migraine patients followed in
neurology clinics in Riyadh, Saudi Arabia. Journal of Family and Community
Medicine. 2020;27(1):37.
Muayqil T, Al-Jafen BN, Al-Saaran Z, Al-Shammari M, Alkthiry A, Muhammad
WS, et al. Migraine and headache prevalence and associated comorbidities in a
large Saudi sample. Eur Neurol. 2018;79:126–34.
Tayel SS. Effect of migraine headache on academic performance and quality of
life of female students at King Saud University, Kingdom of Saudi Arabia. Bull
Alex Fac Med. 2008;44:503–9.
Migraine, tension-type headache, and depression among Saudi female students
in Taif University. Desouky DE, Zaid HA, Taha AA J Egypt Public Health Assoc.
; 94(1):7.
Jumah AM, Hussein M, Khathaami AA, Kojan S, Stovner L, Steiner T. The
prevalence of primary headache disorders in Saudi Arabia. J Neurol Sci.
;333:e499.
Rajeh SA, Awada A, Bademosi O, Ogunniyi A. The prevalence of migraine and
tension headache in Saudi Arabia: A community-based study. Eur J Neurol.
;4:502–6.
AlHarbi FG, AlAteeq MA. Quality of life of migraine patients followed in
neurology clinics in Riyadh, Saudi Arabia. J Fam Community Med.
;27(1):37–45.
Al-Tulaihi BA, Al-Jumah MA. Prevalence of migraine and non-migraine
headache among high school students at the National Guard Housing in Riyadh,
Saudi Arabia. Saudi Med J. 2009 Jan;30(1):120-4.
Al Jumah M, Awada A, Al Azzam S. Headache syndromes amongst
schoolchildren in Riyadh, Saudi Arabia. Headache. 2002 Apr;42(4):281–6.
Facts and figures - The Migraine Trust [Internet]. [cited 2021 Apr 15]. Available
from: https://www.migrainetrust.org/about-migraine/migraine-what-is-it/factsfigures/
Shaik MM, Hassan NB, Tan HL, Gan SH. Quality of Life and Migraine Disability
among Female Migraine Patients in a Tertiary Hospital in Malaysia. BioMed Res
Int. 2015;2015.
Vargas LG. Gender Gap in Migraine: A Feminist Understanding of a
Complicated Health Disparity Bachelor Tucson. University of Arizona; 2019.
Bigal ME, Lipton RB. The epidemiology, burden, and comorbidities of migraine.
Neurol Clin. 2009;27:321–34.
Almalki ZA, Alzhrani MAG, Altowairqi AT, Aljawi YA, Fallatah SA, Assaedi
LM, et al. Prevalence of migraine headache in Taif City, Saudi Arabia. J Clin
Med Res. 2018;10:125–33.
Stewart WF, Linet MS, Celentano DD, Van Natta M, Ziegler D. Age-and sexspecific incidence rates of migraine with and without visual aura. Am J
Epidemiol. 1991;134:1111–20.
Hepp Z, Bloudek LM, Varon SF. Systematic review of migraine prophylaxis
adherence and persistence. J Manag Care Pharm. 2014;20:22–33.
Goadsby PJ, Sprenger T. Current practice and future directions in the prevention
and acute management of migraine. Lancet Neurol. 2010;9:285–98.
Hepp Z, Dodick DW, Varon SF, Gillard P, Hansen RN, Devine EB. Adherence
to oral migraine-preventive medications among patients with chronic migraine.
Cephalalgia. 2015;35:478–88.
Desouky DE, Zaid HA, Taha AA. Migraine, tension-type headache, and
depression among Saudi female students in Taif University. J Egypt Public
Health Assoc. 2019;94:7.
Steiner TJ, Stovner LJ, Vos T, Jensen R, Katsarava Z. Migraine is first cause of
disability in under 50s: Will health politicians now take notice? J Headache Pain.
;19:17.
D’Amico D, Leonardi M, Grazzi L, Curone M, Raggi A. Disability and quality
of life in patients with different forms of migraine. J Headache Pain. 2015;16:A4.
Holmes WF, MacGregor EA, Sawyer JP, Lipton RB. Information about migraine
disability influences physicians’ perceptions of illness severity and treatment
needs. Headache. 2001;41:343–50.
Lipton RB, Hahn SR, Cady RK, Brandes JL, Simons SE, Bain PA, et al. In-office
discussions of migraine: Results from the American migraine communication
study. J Gen Intern Med. 2008;23:1145–51.
Buse DC, Scher AI, Dodick DW, Reed ML, Fanning KM, Manack Adams A, et
al. Impact of Migraine on the Family: Perspectives of People With Migraine and
Their Spouse/Domestic Partner in the CaMEO Study. Mayo Clin Proc. 2016 pii:
S0025-6196 (16) 00126-9.
Rutberg S, Öhrling K. Migraine-more than a headache: Women’s experiences of
living with migraine. DisabilRehabil. 2012;34:329–36.
Katsarava Z, Mania M, Lampl C, Herberhold J, Steiner TJ. Poor medical care for
people with migraine in Europe – Evidence from the Eurolight study. J Headache
Pain. 2018;19:10.
Vosoughi K, Stovner LJ, Steiner TJ, Moradi-Lakeh M, Fereshtehnejad SM,
Farzadfar F, et al. The burden of headache disorders in the Eastern Mediterranean
region, 1990-2016: Findings from the global burden of disease study 2016. J
Headache Pain. 2019;20:40.
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