Distribution pattern of ABO and Rh blood group among blood donors at Hospital Blood Bank in Delhi- An initial step to evaluate preparedness to fight an epidemic

Distribution pattern of ABO and Rh blood group among blood donors

  • Rubeena Naz Mohroo Hamdard Institute of Medical Sciences & Research, Jamia Hmadard, New Delhi
  • Mohammad. Jaseem Hassan Hamdard Institute of Medical Sciences and Research
  • Sabina Khan Hamdard Institute of Medical Sciences & Research, Jamia Hmadard, New Delhi
  • Nehal Ahmad Hamdard Institute of Medical Sciences & Research, Jamia Hmadard, New Delhi
  • Sujata Jetley Hamdard Institute of Medical Sciences & Research, Jamia Hmadard, New Delhi
Keywords: ABO, Blood group, Rhesus, Replacement, Voluntary

Abstract

Introduction: The ABO and Rh blood group systems is most important of all blood groups systems in both blood transfusion and transplant medicine. Antigens present on the surface of RBC’s play an important role in understanding genetics, inheritance pattern, medicolegal issues, disease susceptibility and transfusion safety. It is important to study the distribution of blood group in different population for clinical studies, their relation with disease and environment. The effective management of blood bank and safe transfusion services can be achieved by understanding distribution of ABO and Rh blood groups, as its frequency varies time to time from one population to other.

The aim of present study is to determine the distribution pattern of ABO and Rh blood group among the donors at our hospital so as to assess the preparedness of our blood bank to combat ongoing epidemic and to correlate with other studies carried in different regions of India.

Material and methods: A retrospective study was carried out at our hospital blood bank. The study includes both voluntary and replacement donors. The donors were first screened according to criteria for blood donation. The blood samples were obtained by venepuncture method and Blood grouping ABO and Rhesus was done by antigen antibody micro-agglutination tube test. The data was collected in MS Excel spread sheet coded appropriately and analysed by using Statistical Package for Social Sciences (SPSS) software version 24.

Results: Total number of donors were 7822, among which 7681were males and 141 were females. The most common blood group was B (35.40%) and least common was AB (9.65 %) in both males and females. Incidence of ABO blood group showed B blood groups was commonest (35.40%), followed by blood group O (30.96%), blood group A (23.98%) and the least was blood group AB (9.65%). In Rh grouping, 95.63% donors were Rh positive and 4.37% were Rh negative. The maximum donors belonged to 18 -30 years of age group.

Conclusion: This study helps us to know the exact distribution of blood group in our community, which will ultimately help us to plan accordingly in case of any epidemic or disaster. This study also benefits, by collecting data from different regions of India to prepare for future health challenges and smooth functioning of transfusion services and availability of respective blood groups round the clock and to meet the increase demands, thus preventing mortality associated with non-availability of blood at the time of emergency.

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Author Biographies

Rubeena Naz Mohroo, Hamdard Institute of Medical Sciences & Research, Jamia Hmadard, New Delhi

Demonstrator,

Department of pathology

HIMSR. Jamia Hmdard,

New Delhi.110062

Sabina Khan, Hamdard Institute of Medical Sciences & Research, Jamia Hmadard, New Delhi

Professor

Department of pathology

HIMSR. Jamia Hmdard,

New Delhi.110062

Nehal Ahmad, Hamdard Institute of Medical Sciences & Research, Jamia Hmadard, New Delhi

Assistant Professor

Department of pathology

HIMSR. Jamia Hmdard,

New Delhi.110062

Sujata Jetley, Hamdard Institute of Medical Sciences & Research, Jamia Hmadard, New Delhi

Professor

Department of pathology

HIMSR. Jamia Hmdard,

New Delhi.110062

References

1. Denise M. Harmening, Beth L.Manning. The ABO blood group system. Modern blood banking and transfusion practices.7th ed. F.A. Davis; 2019:119-145.
2. Makroo R.N. The Rh Blood group system. Compendium of transfusion medicine.2nd ed. 2009: 66-77
3. International Society of Blood Transfusion. Red cell immunogenetics and blood group terminology. http:// www.isbtweb.org/ working-parties/ red-cell immunogenetics- and-blood-group-terminology. Accessed on 27 July 2016.
4. Mathew E, Godwin N. Distribution of ABO and Rh-D blood groups in the Benin area of Niger-Delta: Implication for regional blood transfusion. Asian Journal of transfusion Science 2008;2:1-3
5. Manu M, Rishi D. A retrospective study of pattern and frequency of blood groups in voluntary donors attending blood bank of a tertiary care hospital. J Pharm Biomed Sci 2012;21:2230-7885
6. Mallikarjuna S. Prevalence of ABO and Rhesus blood group among blood donors. Indian J Pub Health Research and Development 2012;3:106-109.
7. Shazia H, Samreen S. Distribution of ABO and Rhesus Blood Groups in Kashmir Valley. International Journal of Science and Research 2014;3:233-235.
8. Jiao Zhao, Yan Yang, Hanping Huang, Dong Li, Dongfeng Gu, Xiangfeng Lu et al Relationship between the ABO Blood Group and the COVID-19 Susceptibility. medXRvi preprint, doi: https://doi.org/10.1101/2020.03.11.20031096
9. Pratima V, Shraddha S, Akhilesh K. Prevalence of Heamoglobin Variants, ABO and Rhesus Blood Groups in Northern Uttar Pradesh, India. Biomedical Research 2013;24:377-382.
10. Patel A, Sangeeta P, Shah V, Haren V. Frequency and distribution of Blood Groups in Blood Donors in Western Ahmedabad a hospital based study. National J Med Res 2012; 2:207-210
11. Satish Kumar, Purab Kalyan Modak, S. Haroon Ali, S. K. Barpanda, Vimal Singh Gusain, Rupali Roy. A retrospective study: ABO and Rh phenotype blood group distribution among blood donors in H.N.B. Base Hospital, Srinagar, Uttarakhand, India. Journal of Family Medicine and Primary Care 2018;7:34-38
12. Singh A, Srivastava RK, Deogharia KS, Singh KK. Distribution of ABO and Rh types in voluntary blood donors in Jharkhand area as a study conducted by RIMS, Ranchi. J Family Med Prim Care 2016;5:631‑6.
13. Kaur D, Doda V, Kandwal M, Parmar I. ABO Rh (D) blood group distribution among whole blood donors at two different setups of tertiary care hospitals in North India. Int J Community Med Public Health 2016;3:2806‑11.
14. Chandra T, Gupta A. Frequency of ABO and rhesus blood groups in blood donors. Asian J Transfus Sci. 2012;6:52-53.
15. Kaur H, Khanna A, Manjari M, Khanna M. Prevalence of ABO blood groups and rhesus (Rh) factor in the population residing in and around Amritsar, Punjab (a 4- year study from June 2007 to June 2011). Asian J Transfus Sci. 2013;7:159.
16. Patel Piyush A, Patel Sangeeta P, Shah Jigesh V, Oza Haren V. Frequency and distribution of blood groups inblood donors in western Ahmedabad – a hospital based study. National J. Med. Res. 2012;2:207-210.
17. Wadhwa MK, Patel SM, Kothari DC, Pandey M, Patel DD. Distribution of ABO and Rhesus-D groups in Gujarat, India: a hospital based study. Indian J Ped Oncol.1998;19:137–41.
18. Giri P A, Yadav S, Parhar G S, Phalke DB. Frequency of ABO and Rhesus Blood Groups: A study from a rural tertiary care teaching hospital in India. Int J Biol Med Res. 2011;2:988–90.
19. Mehta AA, Mehta AA. Frequency distribution of ABO blood group and Rh factor in Bhanpur. Bhopal. Sch Acad J Biosci 2016;4:106‑9.
20. Nag I, Das SS. ABO and Rhesus blood groups in potential blood donors at Durgapur Steel city of the district of Burdwan, West Bengal. Asian J. Transfus Sci. 2012;6:54-55.
21. Islam Barbhuiya FG, Rahman M, Ahmed SA. Frequency and distribution of Abo and Rh (D) blood groups among the Bengali Muslims of Cachar District of Assam, India. Asian J Multidiscip Stud 2016;4:2017‑20.
22. Periyavan A, Sangeetha S K, Marimuthu P, Manjunath BK, Seema DM. Distribution of ABO and Rhesus-D, groups in and around Bangalore. Asian J Transfus Sci.2010;4:41.
23. Mallikarjuna S. Prevalence of ABO and Rhesus blood group among blood donors. Indian J. Pub. Health Research and Development. 2012:3:106-09.
24. Girish C J, Chandrashekhar T N, Ramesh Babu K, Kantikar S M. ABO and Rhesus blood group distribution among Malnad region blood donors. Research and Reviews in Biomedicine and Biotechnolog 2011;2:25-30.
25. Dean L. The ABO blood group. In: Blood Groups and Red Cell Antigens. Bethesda (MD): National Center for Biotechnology Information (US); 2005.Available from:http://www.ncbi.nlm.nih.gov/books/NBK2267/
26. Khan MS, Subhan F, Tahir F, Kazi BM, Dil AS, Sultan S. Prevalence of blood groups and Rh factor in Bannu region NWFP (Pakistan). Pak J Med Res. 2004;4:8–10.
27. Giancarlo Maria Liumbruno , Massimo Franchini. Beyond immunohaematology: the role of the ABO blood group in human diseases. Blood Transfus 2013;11:491-9
28. Khan M I, Micheal S, Akhtar F, Naveed A, Ahmed A & Qamar R. Association of ABO blood groups with glaucoma in the Pakistani population. Canadian Journal of Ophthalmology. 2009;44:582–86.
29. Reid ME, Bird GW. Associations between human red cell blood group antigens and disease. Transfus Med Rev. 1990;4:47-55.
30. Wolpin B M, Kraft P, Gross M, Helzlsouer K, Bueno-de-Mesquita H B, Steplowski E. Pancreatic cancer risk and ABO blood group alleles: results from the pancreatic cancer cohort consortium. Cancer Res. 2010;70:1015–23.
31. Gates M A, Wolpin B M, Cramer D W, Hankinson S E, Tworoger S S. ABO blood group and incidence of epithelial ovarian cancer. Int J Cancer. 2010;128:482– 86.
32. Fang-Ming Wang,1 Yan Zhang, Gui-Ming Zhang, Ya-Nan Liu, Li-Jiang Sun, Yong Liu. Association of ABO Blood Types and Clinicopathological Features of Prostate Cancer. Disease Markers 2017;9237481, https://doi.org/10.1155/2017/9237481
33. Cheng Y, Cheng G, Chui CH, Lau FY, Chan PK, Ng MH. ABO blood group and susceptibility to severe acute respiratory syndrome. JAMA. 2005;293(12):1450-1.
34. Guillon P, Clément M, Sébille V, Rivain JG, Chou CF, Ruvoën-Clouet N, Le Pendu J. Inhibition of the interaction between the SARS-CoV spike protein and its cellular receptor by anti-histo-blood group antibodies. Glycobiology. 2008 ;18:1085-93.
35. Parul G, Saloni U, Sanjay S. Prevalence of ABO and Rhesus Blood Groups in Blood Donors: A Study from a Tertiary Care Teaching Hospital of Kumaon Region of Uttarakhand. Journal of Clinical and Diagnostic Research 2014;8:16-19.
Published
2020-09-30
How to Cite
1.
Mohroo RN, Hassan MJ, Khan S, Ahmad N, Jetley S. Distribution pattern of ABO and Rh blood group among blood donors at Hospital Blood Bank in Delhi- An initial step to evaluate preparedness to fight an epidemic. Int Arch BioMed Clin Res [Internet]. 2020Sep.30 [cited 2020Oct.21];6(3):PA3-PA6. Available from: http://iabcr.org/index.php/iabcr/article/view/602
Section
ORIGINAL ARTICLES ~ Pathology