Metabolic Syndrome in Patients of Obsessive-Compulsive Disorder: A Hospital-Based Study

  • Jaya Sharma Assistant Professor, Department of Psychiatry, Govt. Doon Medical College, Dehradun
  • Jeetpal Singh Rana Associate Professor, Department of Psychiatry, Govt. Doon Medical College, Dehradun
Keywords: OCD, metabolic syndrome, fasting blood sugar (FBS), triglycerides.


Background: The prevalence of OCD is around 2-3% in general population. Some research has found it to be 10%. OCD patients are usually affected by other mental disorders also. In OCD patients, the occurrence of major depressive disorder is about 67%.

Methods: Total 328 OCD cases were enrolled on the basis of inclusion and exclusion criteria. This study was conducted in Department of Psychiatry.

Results: In our study we were included total 328 cases of OCD. The sociodemographic study of the cases showed in this study. In this study, Males were 124 in number and females were 204. Married patients outnumber the unmarried with 56.1% married vs. Prevalence of metabolic syndrome in OCD cases was 32.9%.

Conclusions: Mean score for measuring the severity of OCD found to be more in MS patients and it was significant when compared it with patients in which metabolic syndrome was absent (p=0.001).




Download data is not yet available.

Author Biography

Jeetpal Singh Rana, Associate Professor, Department of Psychiatry, Govt. Doon Medical College, Dehradun




1. World Health Organization. Mental Health-Facing the Challenges, Building Solutions:Report from the WHO European Ministerial Conference. World Health Organization;2005.p.1-182.
2. Kaplan, H. I. & Sadock, B. J.Synopsis of psychiatry: Behavioral sciences clinical psychiatry,11th ed.Williams & Wilkins Co;2015.p.418
3. Hert M, Schreurs V, Vancampfort D, Winkel R. Metabolic syndrome in people with schizophrenia: a review. World psychiatry 2009;8:15-22.
4. Mitchell AJ, Vancampfort D, Sweers K, van Winkel R, Yu W, De Hert M et al. Prevalence of metabolic syndrome and metabolic abnormalities in schizophrenia and related disorders—a systematic review and meta-analysis. Schizophrenia bulletin 2013;39: 306-18.
5. Ravindranath BV. Metabolic syndrome in patients with severe mental illness undergoing psychiatric rehabilitation receiving high dose antipsychotic medication. Indian journal of psychological medicine 2012;34:247.
6. Grover S, Malhotra N, Chakrabarti S, Kulhara P. Metabolic syndrome in bipolar disorders. Indian journal of psychological medicine;34:110.
7. Newcomer JW. Metabolic syndrome and mental illness. The American journal of managed care 2007;13:S170-7.
8. Kato MM, Gonzalez-Blanco M, Sotelo JL, Ferreira G, Tuckler A, Currier B. Metabolic syndrome in schizophrenia: a pilot study. In Abstract Presented at the American Psychiatric Association Annual Meeting, San Francisco 2003 May 17.
9. Kato M, Sotelo J, de Guia C. Prevalence of the metabolic syndrome in Hispanic patients with mood disorder: a pilot study. In156th annual meeting of the American Psychiatric Association 2003 May 17.
10. Kessler RC, Berglund P, Chiu WT, Demler O, Heeringa S, Hiripi E, et al. The US National Comorbidity Survey Replication (NCS-R): design and field procedures. Int J Methods Psych Res. 2004;13:69–92.
11. Mansur RB, Brietzke E, McIntyre RS. Is there a “metabolic-mood syndrome”? A review of the relationship between obesity and mood disorders. Neurosci Bio Behav Rev. 2015;52:89–104.
12. Magalhaes PV, Kapczinski F, Nierenber AA, Deckersbach T, Weisinger D, Dodd S, et al. Illness burden and medical comorbidity in the Systematic Treatment Enhancement Program for Bipolar Disorder. Acta Psychiatr Scand. 2012;125:303–308.
13. Crump C, Sundquist K, Winkleby MA, Sundquist J. Comorbidities and mortality in bipolar disorder: a Swedish national cohort study. JAMA Psychiatry. 2013;70:931–939.
14. Cosci F, Fava GA, Sonino N. Mood and anxiety disorders as early manifestations of medical illness: a systematic review. Psychother Psychosom. 2015;84:22–29.
15. .Hosseinpour-Niazi S, Mirmiran P, Hosseinpanah F, Fallah-ghohroudy A, Azizi F. Association of marital status and marital transition with metabolic syndrome: Tehran lipid and glucose study. International journal of endocrinology and metabolism 2014;2.
16. Maina G, Salvi V, Vitalucci A, D'Ambrosio V, Bogetto F. Prevalence and correlates of overweight in drug-naïve patients with bipolar disorder. Journal of affective disorders 2008;110: 149-155.
17. Ali NS, Khuwaja AK, Nanji K. Retrospective analysis of metabolic syndrome: Prevalence and distribution in executive population in urban Pakistan. International journal of family medicine 2012.
18. Regitz-Zagrosek V, Lehmkuhl E, Weickert MO. Gender differences in the metabolic syndrome and their role for cardiovascular disease. Clinical Research in Cardiology 2006;95:147.
19. Das S, O’Keefe JH. Behavioral cardiology: recognizing and addressing the profound impact of psychosocial stress on cardiovascular health. Current hypertension reports 2008;10:374-81.
How to Cite
Sharma J, Rana JS. Metabolic Syndrome in Patients of Obsessive-Compulsive Disorder: A Hospital-Based Study. Int Arch BioMed Clin Res [Internet]. 2020Jun.29 [cited 2020Jul.11];6(2):PS1-PS3. Available from: