Use of Adenosine and Magnesium Sulphate Vs Bupivacaine in Upper Limb Surgeries and Post-Operative Analgesia: A Comparative Hospital Based Study

  • Suraj Kumar Assistant Professor, Department of Anaesthesiology , Dr. Ram Manohar Lohia Institute of Medical Sciences Gomti Nagar, Lucknow
  • Anurag Agarwal Associate Professor, Department of Anaesthesiology , Dr. Ram Manohar Lohia Institute of Medical Sciences Gomti Nagar, Lucknow
  • Shivani Rastogi Associate Professor, Department of Anaesthesiology , Dr. Ram Manohar Lohia Institute of Medical Sciences Gomti Nagar, Lucknow
  • P K Das Professor (Junior Grade), Department of Anaesthesiology , Dr. Ram Manohar Lohia Institute of Medical Sciences Gomti Nagar, Lucknow
  • Mamta Harjai Professor (Junior Grade), Department of Anaesthesiology , Dr. Ram Manohar Lohia Institute of Medical Sciences Gomti Nagar, Lucknow
  • Deepak Malviya Professor and Head, Department of Anaesthesiology , Dr. Ram Manohar Lohia Institute of Medical Sciences Gomti Nagar, Lucknow
Keywords: Bupivacaine, Adenosine, Magnesium Sulfate

Abstract

Background: The present study was conducted to compare the additives adenosine and magnesium sulphate with bupivacaine in infraclavicular infusion for upper limb surgeries and postoperative analgesia

Methods: This Prospective study was done at the Department of Anaesthesiology. Around 26 patients scheduled for elective unilateral upper limb surgeries involving distal arm/ elbow/ forearm/hand divided into two groups A (n=13) and B (n=13) randomly. Group A - adenosine 6mgs with 28 ml 0.5% bupivacaine bolus followed by infusion of 0.25% bupivacaine 28ml with 6mgs of adenosine (2ml) at a rate of 5ml/hr. Group B - magnesium sulphate 75 mgs (in 2ml) with 28ml of 0.5% bupivacaine bolus followed by infusion of 0.25% bupivacaine 28ml with 75mgs of magnesium sulphate (in 2ml) at a rate of 5ml/hr in USG guided placement of infraclavicular catheter.

Results: Result  showed  that  Group  A  had a  faster Onset time of sensory and motor block and faster recovery as compared to group B. Group A needed more rescue analgesia than group B..

Conclusions: The addition of magnesium sulphate as an additive to bupivacaine in brachial plexus block may be a better choice when prolonged postoperative analgesia is required.

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References

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How to Cite
1.
Kumar S, Agarwal A, Rastogi S, Das PK, Harjai M, Malviya D. Use of Adenosine and Magnesium Sulphate Vs Bupivacaine in Upper Limb Surgeries and Post-Operative Analgesia: A Comparative Hospital Based Study. Int Arch BioMed Clin Res [Internet]. 1 [cited 2020May28];6(1):AN4-AN6. Available from: http://iabcr.org/index.php/iabcr/article/view/574
Section
ORIGINAL ARTICLES ~ Anaesthesiology