Use of Adenosine and Magnesium Sulphate Vs Bupivacaine in Upper Limb Surgeries and Post-Operative Analgesia: A Comparative Hospital Based Study
Background: The present study was conducted to compare the additives adenosine and magnesium sulphate with bupivacaine in infraclavicular infusion for upper limb surgeries and postoperative analgesia
Methods: This Prospective study was done at the Department of Anaesthesiology. Around 26 patients scheduled for elective unilateral upper limb surgeries involving distal arm/ elbow/ forearm/hand divided into two groups A (n=13) and B (n=13) randomly. Group A - adenosine 6mgs with 28 ml 0.5% bupivacaine bolus followed by infusion of 0.25% bupivacaine 28ml with 6mgs of adenosine (2ml) at a rate of 5ml/hr. Group B - magnesium sulphate 75 mgs (in 2ml) with 28ml of 0.5% bupivacaine bolus followed by infusion of 0.25% bupivacaine 28ml with 75mgs of magnesium sulphate (in 2ml) at a rate of 5ml/hr in USG guided placement of infraclavicular catheter.
Results: Result showed that Group A had a faster Onset time of sensory and motor block and faster recovery as compared to group B. Group A needed more rescue analgesia than group B..
Conclusions: The addition of magnesium sulphate as an additive to bupivacaine in brachial plexus block may be a better choice when prolonged postoperative analgesia is required.
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