A Prospective Study on Assessment of HbA1c Level and Lipid Profile in the Development of Type 2 Diabetes Mellitus

  • Tushar Vasudev Vyas Associate Prof., Department of Medicine, AIIMS, Udaipur
Keywords: Dyslipidaemia, Type 2 Diabetes Mellitus, Risk factor.

Abstract

Background: Dyslipidaemia due to insulin resistance, the major cause of coronary atherosclerosis and ischemic heart disease is frequently associated with type 2 diabetes mellitus. Type 2 diabetes mellitus is an emerging pandemic with the number of patients increasing rapidly in both developed and developing countries around the world.

Methods: This study was carried out in the  Department of Medicine, AIIMS, Udaipur. 80 males of type 2 Diabetes Mellitus were selected on the basis of inclusion and exclusion criteria. Enrolled patients will be investigated for HbA1C and lipid profile. Results: In the present study, dyslipidaemia was found to be present in 85% patients of type 2 diabetes mellitus. Of these, 24% had single abnormal lipid parameter while 72% had combined dyslipidaemia.. Conclusions: Prevalence of dyslipidaemia was alarmingly high in type 2 diabetes mellitus patients. Thus, HbA1C can be considered as a marker of dyslipidaemia in type 2 diabetes mellitus.

Downloads

Download data is not yet available.

References

1. Gaziano TA, Gaziano JM. Global burden of cardiovascular diseases. In: Bonow RO, Mann DL Zipes DP, Libby P editors. Braunwald’s Heart Disease: A textbook of Cardiovascular Medicine. Philadelphia: Saunders-Elsevier 2012;9:1-12
2. Gaziano TA, Gaziano JM. Global burden of cardiovascular diseases. In: Bonow RO, Mann DL Zipes DP, Libby P editors. Braunwald’s Heart Disease: A textbook of Cardiovascular Medicine. Philadelphia: Saunders-Elsevier 2012;9:1-12
3. Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA et al. Association of glycemia with macrovascular and microvascular complications of type 2 diabetes: prospective observational study. British Medical Journal 2000;321:405-412
4. Turner RC, Millns H, Neil NA, Stratton IM, Manley SE, Matthews DR et al. Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus: United Kingdom Prospective Diabetes Study. British Medical Journal 1998;316:823-828
5. Ramaiya KL, Kodali VR, Alberti K. Epidemiology of diabetes in Asians of the Indian subcontinent. Diabetes Metabolism Review. 1990;6:125-146
6. National Cholesterol Education Programme (NCEP) Adult Treatment Panel III (A TP III) guideline. http://www.nhlbi.nih.gov/guidelines/cholesterol/index.htm as visited on 19/9/13
7. Mahato RV, Gyawali P, Raut PP, Regmi P, Singh KP, Pandeya DR et al. Association between glycaemic control and serum lipid profile in type 2 diabetic patients: Glycated haemoglobin as a dual biomarker. Biomed Res. 2011;22(3):375-80.
8. Sreenivas RA, Meera S, Ebenezer W, Kumar JS. Correlation between glycemic control and lipid profile in type 2 diabetic patients: HbA1C an indirect indicator of dyslipidaemia. Asian J Pharma Clin Res. 2014;7(2):153-155
Published
2020-03-29
How to Cite
1.
Vyas TV. A Prospective Study on Assessment of HbA1c Level and Lipid Profile in the Development of Type 2 Diabetes Mellitus. Int Arch BioMed Clin Res [Internet]. 2020Mar.29 [cited 2020May28];6(1):GM11-GM13. Available from: http://iabcr.org/index.php/iabcr/article/view/568
Section
ORIGINAL ARTICLES ~ General Medicine