Evaluation of Hematological Abnormalities in HIV Patients in Kosi Zone of Bihar
DOI:
https://doi.org/10.21276/njp0c033Keywords:
HIV, Thrombocytopenia, LeucopeniaAbstract
Background: Hematological abnormalities are among the most common complications of HIV. Anaemia is the most common hematological abnormality in HIV patients, and is strongly associated with the progression of the disease, followed by leucopenia and thrombocytopenia. The objective of the study is to find out the magnitude & type of hematological abnormalities and its correlation to CD4 Count. Methods: The study was done on 80 HIV patients, above the age of 15 yrs, including both males and females, attending ART Centre, at Katihar Medical College, Katihar, Bihar. Various haematological parameters were recorded and studied with respect to CD4 count. Results: Among the total patients, 57.5% had anaemia, 23.75% had leucopenia and 12.5% had thrombocytopenia. The magnitude of these abnormalities were directly proportional to low CD4 counts. Results: Among the total patients, 57.5% had anaemia, 23.75% had leucopenia and 12.5% had thrombocytopenia. The magnitude of these abnormalities were directly proportional to low CD4 counts.
Conclusions: These hematological parameters can be used to assess the severity and progression of HIV as they are directly associated with CD4 count. Anaemia being the single most independent factor associated with high mortality. Aggressive treatment of these haematological abnormalities can lead to substantial decline in morbidity and mortality associated with HIV patients.
Downloads
References
De Santis GC, Brunetta DM, Vilar FC, Brandão RA, de Albernaz Muniz RZ, de Lima GM, et al. Hematological abnormalities in HIV-infected patients. Int J Infect Dis 2011;15:808-11.
Servais J, Nkoghe D, Schmit JC, Arendt V, Robert I, Staub T, et al. HIV-Associated Hematologic Disorders Are Correlated With Plasma Viral Load and Improve Under Highly Active Antiretroviral Therapy. J Acquir Immune Defic Syndr 2001; 28(3):221-225.
NACO annual report of 2014-15.
Rios A. HIV-related hematological malignancies: A concise review. Clin Lymphoma Myeloma Leuk 2014;14:S96-103.
Oral lesions and conditions associated with HIV infection in 1000 HIV patients. K Ranganathan, Ann acad Med Singapore 2004.
Hematological outline in HIV infection in relation to CD4 cell count, a hospital based study Vanisri HR, Vadiraja N Mysore Medical College & Research Institute, Mysore. Indian Journal of Pathology and Oncology, April-June 2016;3(2);260-263
Profile of hematological abnormalities of Indian HIV infected Individuals Byomakesh Dikshit, Ajay Wanchu, Ravinder Kaur Sachdeva, Aman Sharma BMC Blood Disorders 2009doi:10.1186/1471-2326-9.
The prevalence of HIV seropositivity and associated cytopenias in full blood counts processed at an academic laboratory in Soweto, South Africa; J L Vaughan et al; S Afr Med J 2017;107(3):264-269. DOI:10.7196/SAMJ.2017.v107i3.11206.
N. H. Santosh, Velho G. Rachita, Kotha Sindhoora, Cacodcar Jagadish. "Clinical profile of Anaemia among HIV Infected Patients and its Correlation with CD4+ Count". Journal of Evolution of Medical and Dental Sciences 2015; Vol. 4, Issue 62, August 03; Page: 10795-10802, DOI: 10.14260/jemds/2015/1558.
Hematological Manifestations in HIV Infected Patients and Correlation with CD4 Counts and Anti Retroviral Therapy; Swati Kathuria1, Permeet Kaur Bagga2, Sita Malhotra3; International Journal of Contemporary Medical Research; Volume 3 | Issue 12 | December 2016 | ICV (2015): 77.83.
To Study the Hematological parameters as predictors of morbidity in patients with HIV infection: Imtiaz Pasha; GLOBAL JOURNAL OF MEDICINE AND PUBLIC HEALTH; 2014; Vol. 3, issue 1.
Haematological changes in HIV infection with correlation to CD4 cell count. SS Parinitha and MH Kulkarni, Australasian Medical Journal [AMJ 2012, 5, 3, 157-162].
Jayanti Chandrakar, Rabia P. Siddiqui, Mamta Singh. "Haematological Profile of HIV Seropositive Patients in Relation to CD4 Lymphocyte Count". Journal of Evidence based Medicine and Healthcare; Volume 2, Issue 39, September 28, 2015; Page: 6399-6405, DOI: 10.18410/jebmh/2015/876.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 International Archives of BioMedical and Clinical Research
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors are required to sign and submit the completed “Copyright transfer Form” upon acceptance of publication of the paper. This is determined by a publishing agreement between the author and International Archives of Biomedical and Clinical Research. These rights might include the right to publish, communicate and distribute online. Author(s) retain the copyright of their work. International Archives of Biomedical and Clinical Research supports the need for authors to share, disseminate and maximize the impact of their research.
